FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\eschs.PS
Open Close
General Information
Symbol
Dmel\eschs.PS
Species
D. melanogaster
Name
heat shock construct of Simon
FlyBase ID
FBal0060425
Feature type
allele
Associated gene
Dmel\esc
Associated Insertion(s)
Carried in Construct
P{cHSesc}
Key Links
Transgenic product class
cDNA
(Simon et al., 1995)
wild_type
(Simon et al., 1995)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Simon et al., 1995)
wild_type
(Simon et al., 1995)
Mutagen
in vitro construct
(Simon et al., 1995)
Progenitor genotype
Carried in construct
P{cHSesc}
Cytology
Description

1.5kb DraI fragment of esc e2 cDNA (containing the entire open reading frame, 84bp of 5'UTR DNA and 163bp of 3'UTR DNA) fused downstream of an Hsp70 heat inducible promoter.

(Simon et al., 1995)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
esc
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Single or repeated heat shocks during development allow flies to survive to adulthood with no segment transformations.

      (Simon et al., 1995)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      eschs.PS partially rescues esc2/Df(2L)esc10

      (Simon et al., 1995)
      Comments

      Rescue to first instar larval viability is seen if heat shock is induced prior to 4 hours of embryogenesis. Only 10% of rescued larvae reach adulthood. Of these adults half are normal and half exhibit segmental transformations.

      (Simon et al., 1995)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      eschs.PS
      Name Synonyms
      heat shock construct of Simon
      (Simon et al., 1995)
      Secondary FlyBase IDs
        References (1)