FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\kluhs.PY
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General Information
Symbol
Dmel\kluhs.PY
Species
D. melanogaster
Name
heat shock construct of Yang
FlyBase ID
FBal0061358
Feature type
allele
Associated gene
Dmel\klu
Associated Insertion(s)
Carried in Construct
P{hsp70-klu.Y}
Key Links
Transgenic product class
cDNA
(Yang et al., 1997)
wild_type
(Yang et al., 1997)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Yang et al., 1997)
wild_type
(Yang et al., 1997)
Mutagen
in vitro construct
(Yang et al., 1997)
Progenitor genotype
Carried in construct
P{hsp70-klu.Y}
Cytology
Description

A full length klu cDNA is expressed under the control of an Hsp70 promoter.

(Yang et al., 1997)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
klu
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies in which kluhs.PY is expressed in a burst using heat shock at 23, 24, 25 or 26 hours after puparium formation have a reduction in the number of cells surrounding each ommatidial core.

      (Rusconi et al., 2004)

      Ectopic expression of kluhs.PY by heat shock reduces the number of mature RP2 neurons in late embryos. Heat shock treatment at stage 10 results in the maximal loss of mature RP2 neurons.

      (Yang et al., 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      kluhs.PY
      Name Synonyms
      heat shock construct of Yang
      (Yang et al., 1997)
      Secondary FlyBase IDs
        References (2)