FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Orc2γ3
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General Information
Symbol
Dmel\Orc2γ3
Species
D. melanogaster
Name
FlyBase ID
FBal0061700
Feature type
allele
Associated gene
Dmel\Orc2
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
gamma ray
(Landis et al., 1997)
Progenitor genotype
Cytology

Polytene chromosomes normal.

(Landis et al., 1997)
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Orc2γ3/+ stage 13 egg chambers show a slight reduction in the intensity of BrdU-labelled foci in some follicle cells compared to wild type.

      (Cayirlioglu et al., 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Orc2[+]/Orc2γ3 is a suppressor | partially of follicle cell phenotype of E2f21-188, E2f2329

      (Cayirlioglu et al., 2003)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The ectopic genomic replication that is seen in the follicle cells of stage 13 E2f2329/E2f21-188 egg chambers is partially suppressed by Orc2γ3/+; there is an approximate 65% reduction in the number of follicle cells within an egg chamber that display ectopic genomic replication and there is an apparent reduction in the intensity of ectopic BrdU incorporation.

      (Cayirlioglu et al., 2003)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Orc2γ3
      (Cayirlioglu et al., 2003)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)