FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Ddcunspecified
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General Information
Symbol
Dmel\Ddcunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0063512
Feature type
allele
Associated gene
Dmel\Ddc
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    (FlyBase Curators, 2025-)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Homozygous clones result in lightly pigmented triple row bristles. Homozygous clones in the abdomen result in lightly pigmented cuticle and bristles. Homozygotes for a temperature-sensitive Ddc allele which are raised at 25o or 29oC have very thin wispy hairs on the wing, occasional multiple hair cells and the wing has an overall faint appearance.

        (Ren et al., 2005)

        Somatic clones exhibit an albino phenotype in both cuticle and bristles.

        (True et al., 1999)

        Irregularity of heart rhythm is pronounced compared to wild-type and the heart rate is significantly lower than wild-type in homozygous Ddcunspecified animals tested at the transition between larva and pupa at 20, 25, 30, 35 or 37oC.

        (Johnson et al., 1997)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Other
        Statement
        Reference

        AsnRS38, Ddcunspecified has lethal phenotype

        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        Ddcunspecified
        unspecified
        (Johnson et al., 1997)
        Name Synonyms
        Secondary FlyBase IDs
          References (4)