FlyBase Allele Report: Dmel\Reph[k16918]

General Information

Symbol

Dmel\Reph^k16918

Species

D. melanogaster

Name

FlyBase ID

FBal0064033

Feature type

allele

Associated gene

Dmel\Reph

Associated Insertion(s)

P{lacW}Reph^k16918

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(BDGP Project Members, 1994-1999)

Progenitor genotype

Associated Insertion(s)

P{lacW}Reph^k16918

Cytology

Description

Insertion within the 5' UTR of the 3.1 kb Reph transcript.

(Dearborn et al., 2012)

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2L:3,806,114..3,806,114 [-]

(Dearborn et al., 2012, Spradling et al., 1999, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | embryonic stage

(Dearborn et al., 2012)

lethal | recessive

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

lethal - all die during embryonic stage

(Dearborn et al., 2012)

partially lethal - majority die (with Reph¹)

(Dearborn et al., 2012)

some die during embryonic stage

(Dearborn et al., 2012)

Phenotype Manifest In

larval longitudinal connective | embryonic stage

(Dearborn et al., 2012)

symmetrical commissure | embryonic stage

(Dearborn et al., 2012)

Detailed Description

Statement

Reference

Frequent defects in the ladder-like organization of commissural and longitudinal connectives are observed in homozygous embryos.

(Dearborn et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

11212

y¹ w^67c23; P{lacW}Reph^k16918/CyO

Kyoto

111366

y^d2 w¹¹¹⁸ P{ey-FLP.N}2 P{5xglBS-lacZ.38-1}TPN1; P{lacW}Reph^k16918 P{neoFRT}40A/CyO y⁺

Notes on Origin

Discoverer

I. Kiss.

(BDGP Project Members, 1994-1999)

Comments

Complements: slp1⁰⁵⁹⁶⁵. Complements: l(2)06708⁰⁶⁷⁰⁸. Complements: l(2)k07315^k07315. Complements: l(2)k08617^k08617.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Reph^k16918

l(2)k16918

(Spradling et al., 1999)

l(2)k16918^k16918

reph^k16918

(Dearborn et al., 2012)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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