FlyBase Allele Report: Dmel\emb[k06303]

General Information

Symbol

Dmel\emb^k06303

Species

D. melanogaster

Name

FlyBase ID

FBal0064043

Feature type

allele

Associated gene

Dmel\emb

Associated Insertion(s)

P{lacW}emb^k06303

Carried in Construct

Also Known As

l(2)K06303

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(BDGP Project Members, 1994-1999)

Progenitor genotype

Associated Insertion(s)

P{lacW}emb^k06303

Cytology

Description

P{lacW} insertion in exon 4.

(Collier et al., 2000)

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2L:8,406,376..8,406,855 [+]

(Collier et al., 2000, Spradling et al., 1999, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

lethal - all die before end of larval stage (with Df(2L)N22-14)

(Collier et al., 2000)

some die during larval stage (with Df(2L)N22-14)

(Collier et al., 2000)

Phenotype Manifest In

Detailed Description

Statement

Reference

The most advanced stage seen in emb^k06303/Df(2L)N22-14 animals is the 2nd larval instar.

(Collier et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

emb^k16715

(BDGP Project Members, 1994-1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Kyoto

102459

y¹ w^67c23 ; P{lacW}emb^k06303 / CyO

Notes on Origin

Discoverer

I. Kiss.

(BDGP Project Members, 1994-1999)

Comments

Despite the P{lacW}emb^k06303 insertion being within 200bp of the fy transcription start site, it does not significantly compromise fy expression; flies heterozygous for P{lacW}emb^k06303 and an amorphic fy allele have no detectable tissue polarity phenotype when cultured at the restrictive temperature.

(Collier et al., 2000)

Complements: l(2)01482⁰¹⁴⁸². Complements: l(2)k07118b^k07118b.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

emb^k06303

l(2)K06303

(Collier et al., 2000)

l(2)k06303

(Spradling et al., 1999)

l(2)k16715^k06303

(BDGP Project Members, 1994-1999)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

Open Close