Open Close
General Information
Symbol
Dmel\geminink14019
Species
D. melanogaster
Name
FlyBase ID
FBal0064112
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
l(2)k14019
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

P{lacW} insertion at +104bp relative to the transcription start site.

Insertion components
P{lacW}geminink14019
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Lethal phase is during embryogenesis/larval stages. 40% of geminink14019/Df(2R)ST1 animals die before hatching and the rest die during larval development (third instar larvae are occasionally seen). 100% of stage 12 geminink14019/geminink09107 ovaries show strong BrdU labeling in 4 amplification foci in all follicle cells (wild-type ovaries at this stage mostly have only one focus of DNA amplification per cell). By stage 14, all follicle cells of wild-type ovaries have ceased DNA amplification, but many follicle cells from 50% of mutant ovaries still continue DNA amplification.

Lethality occurs during third instar larval or pupal stages. Mutants exhibit visible disc abnormalities: very small or no discs. Clones cannot be induced in wild type discs. In tergites, clones with normal size and but lower than expected frequency are recovered. Clones cannot be recovered in the wing disc.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference
Phenotype Manifest In
Enhancer of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

geminink14019/+ causes a significant worsening of the notched wing phenotype resulting from the expression of phlScer\UAS.F179 via Scer\GAL4bbg-C96.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
Comments
Comments

Complements: Adf101349. Complements: Adf104065. Complements: l(2)04535b04535b. Complements: l(2)1052110521. Complements: Adf1k00620. Complements: l(2)04535bk01601. Complements: l(2)k09107k09107. Complements: l(2)04535bk09819. Complements: Adf1k09919. Complements: l(2)04535bk14807.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (6)