FlyBase Allele Report: Dmel\Ehbp1[k09837]

General Information

Symbol

Dmel\Ehbp1^k09837

Species

D. melanogaster

Name

FlyBase ID

FBal0064254

Feature type

allele

Associated gene

Dmel\Ehbp1

Associated Insertion(s)

P{lacW}Ehbp1^k09837

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(BDGP Project Members, 1994-1999)

Progenitor genotype

Associated Insertion(s)

P{lacW}Ehbp1^k09837

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:17,015,775..17,015,775 [+]

(Giagtzoglou et al., 2012, Spradling et al., 1999, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

lethal - all die before end of larval stage (with Df(2R)Exel6065)

(Giagtzoglou et al., 2012)

lethal - all die before end of larval stage (with Ehbp1^A28)

(Giagtzoglou et al., 2012)

lethal - all die before end of larval stage (with Ehbp1^N8)

(Giagtzoglou et al., 2012)

lethal - all die before end of larval stage (with Ehbp1^O4)

(Giagtzoglou et al., 2012)

lethal - all die before end of larval stage (with Ehbp1^T14)

(Giagtzoglou et al., 2012)

lethal - all die before end of larval stage (with Ehbp1^ΔEx24)

(Giagtzoglou et al., 2012)

lethal - all die before end of larval stage | recessive

(Giagtzoglou et al., 2012)

some die during third instar larval stage (with Df(2R)Exel6065)

(Giagtzoglou et al., 2012)

some die during third instar larval stage (with Ehbp1^A28)

(Giagtzoglou et al., 2012)

some die during third instar larval stage (with Ehbp1^N8)

(Giagtzoglou et al., 2012)

some die during third instar larval stage (with Ehbp1^O4)

(Giagtzoglou et al., 2012)

some die during third instar larval stage (with Ehbp1^T14)

(Giagtzoglou et al., 2012)

some die during third instar larval stage (with Ehbp1^ΔEx24)

(Giagtzoglou et al., 2012)

some die during third instar larval stage | recessive

(Giagtzoglou et al., 2012)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Ehbp1^k09837 is rescued by Ehbp1^+t9.1

(Giagtzoglou et al., 2012)

Ehbp1^k09837/Ehbp1^A28 is rescued by Ehbp1^+t9.1

(Giagtzoglou et al., 2012)

Ehbp1^k09837/Ehbp1^O4 is rescued by Ehbp1^+t9.1

(Giagtzoglou et al., 2012)

Ehbp1^k09837/Ehbp1^N8 is rescued by Ehbp1^+t9.1

(Giagtzoglou et al., 2012)

Ehbp1^k09837/Ehbp1^T14 is rescued by Ehbp1^+t9.1

(Giagtzoglou et al., 2012)

Ehbp1^k09837/Df(2R)Exel6065 is rescued by Ehbp1^+t9.1

(Giagtzoglou et al., 2012)

Ehbp1^k09837/Ehbp1^ΔEx24 is rescued by Ehbp1^+t9.1

(Giagtzoglou et al., 2012)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

10931

y¹ w^67c23; P{lacW}Ehbp1^k09837/CyO

Kyoto

114349

y^d2 w¹¹¹⁸ P{ey-FLP.N}2 P{5xglBS-lacZ.38-1}TPN1; P{neoFRT}42D P{lacW}Ehbp1^k09837 /CyO y⁺

Notes on Origin

Discoverer

I. Kiss.

(BDGP Project Members, 1994-1999)

Comments

Complements: l(2)k07408^k07408. Complements: l(2)k13704^k13704.

(BDGP Project Members, 1994-1999)

Precise excision of the insertion reverts the lethal phenotype.

(Giagtzoglou et al., 2012)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Ehbp1^k09837

(Vrailas-Mortimer et al., 2021)

l(2)k09837

(Spradling et al., 1999)

l(2)k09837^k09837

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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