FlyBase Allele Report: Dmel\edl[k12907]

General Information

Symbol

Dmel\edl^k12907

Species

D. melanogaster

Name

FlyBase ID

FBal0064430

Feature type

allele

Associated gene

Dmel\edl

Associated Insertion(s)

P{lacW}edl^k12907

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

loss of function allele

Mutagen

P-element activity

Nature of the Allele

Allele class

loss of function allele

(Baker et al., 2001)

Mutagen

P-element activity

(BDGP Project Members, 1994-1999)

Progenitor genotype

Associated Insertion(s)

P{lacW}edl^k12907

Cytology

Description

Insertion of P{lacW} into the 5'UTR of the edl transcription unit 50bp upstream of the edl initiation codon.

(Baker et al., 2001)

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:18,668,412..18,668,412 [-]

(Baker et al., 2001, Spradling et al., 1999, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Baker et al., 2001, Spradling et al., 1999, BDGP Project Members, 1994-1999)

Phenotype Manifest In

denticle belt & embryonic abdominal segment 1

(Baker et al., 2001)

denticle belt & embryonic abdominal segment 2

(Baker et al., 2001)

denticle belt & embryonic abdominal segment 3

(Baker et al., 2001)

denticle belt & embryonic abdominal segment 4

(Baker et al., 2001)

embryonic ventral epidermis & embryonic abdominal segment 1

(Baker et al., 2001)

embryonic ventral epidermis & embryonic abdominal segment 2

(Baker et al., 2001)

embryonic ventral epidermis & embryonic abdominal segment 3

(Baker et al., 2001)

embryonic ventral epidermis & embryonic abdominal segment 4

(Baker et al., 2001)

Detailed Description

Statement

Reference

Denticle belts are narrowed along the midline, in abdominal segments 1 to 4. This is reminiscent of phenotypes shown by rho and pnt mutant embryos.

(Baker et al., 2001)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

edl^k06602

(BDGP Project Members, 1994-1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Kyoto

102845

y¹ w^67c23 ; P{lacW}edl^k12907 / CyO

Notes on Origin

Discoverer

I. Kiss.

(BDGP Project Members, 1994-1999)

Comments

Complements: l(2)08717⁰⁸⁷¹⁷. Complements: l(2)08770⁰⁸⁷⁷⁰.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

edl^k12907

l(2)k06602^k12907

(BDGP Project Members, 1994-1999)

l(2)k12907

(Spradling et al., 1999)

mae^k12907

(Baker et al., 2001)

mae^l(2)k12907

(Melen et al., 2005)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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