FlyBase Allele Report: Dmel\Ttd14[k04808]

General Information

Symbol

Dmel\Ttd14^k04808

Species

D. melanogaster

Name

FlyBase ID

FBal0064528

Feature type

allele

Associated gene

Dmel\Ttd14

Associated Insertion(s)

P{lacW}Ttd14^k04808

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(BDGP Project Members, 1994-1999)

Progenitor genotype

Associated Insertion(s)

P{lacW}Ttd14^k04808

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:18,440,447..18,440,447 [+]

(Kahsai et al., 2016, Spradling et al., 1999, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal (with Df(2R)BSC335)

(Kahsai et al., 2016)

lethal | recessive

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

partially lethal (with Ttd14^EY01823)

(Kahsai et al., 2016)

partially lethal (with Ttd14^KG03769)

(Kahsai et al., 2016)

Phenotype Manifest In

embryonic/larval crystal cell

(Milchanowski et al., 2004)

embryonic/larval plasmatocyte

(Milchanowski et al., 2004)

Detailed Description

Statement

Reference

The average number of crystal cells per embryo is reduced (to 21.2) in homozygous stage 13-14 embryos compared to wild type (36 +/- 2.2 cells on average). The crystal cells are also mislocalised. The plasmatocytes are also mislocalised in mutant stage 13-14 embryos, being clustered in the anterior third of the embryo (normally they are distributed evenly throughout the entire embryo).

(Milchanowski et al., 2004)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions