FlyBase Allele Report: Dmel\ttk[88.hs.sev.Tag:MYC]

General Information

Symbol

Dmel\ttk^{88.hs.sev.Tag:MYC}

Species

D. melanogaster

Name

FlyBase ID

FBal0082126

Feature type

allele

Associated gene

Dmel\ttk

Associated Insertion(s)

Carried in Construct

P{sev-ttk88}

Key Links

Transgenic product class

wild_type

(Tang et al., 1997)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Tang et al., 1997)

Mutagen

in vitro construct

(Tang et al., 1997)

Progenitor genotype

Carried in construct

P{sev-ttk88}

Cytology

Description

The ttk TTK88 protein isoform, with a C-terminal Tag:MYC tag, is expressed under the control of a sev enhancer.

(Tang et al., 1997)

Allele components

Component

Use(s)

Regulatory region(s)

sev

Encoded product / tool

ttk

Tagged with

Tag:MYC

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible

(Tang et al., 1997)

Phenotype Manifest In

eye

(Tang et al., 1997)

eye photoreceptor cell

(Tang et al., 1997)

Detailed Description

Statement

Reference

Flies carrying ttk^{88.hs.sev.T:Hsap\MYC} have moderately rough eyes, with approximately three missing photoreceptor cells per ommatidium.

(Tang et al., 1997)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

phyl^hs.sev, ttk^{88.hs.sev.Tag:MYC} has visible phenotype

(Tang et al., 1997)

Phenotype Manifest In

Suppressed by

Statement

Reference

ttk^{88.hs.sev.Tag:MYC} has phenotype, suppressible by lilli^XS407

(Tang et al., 2001)

ttk^{88.hs.sev.Tag:MYC} has phenotype, suppressible by lilli^s35

(Tang et al., 2001)

ttk^{88.hs.sev.Tag:MYC} has phenotype, suppressible by lilli^XS575

(Tang et al., 2001)

Other

Statement

Reference

phyl^hs.sev, ttk^{88.hs.sev.Tag:MYC} has eye phenotype

(Tang et al., 1997)

Additional Comments

Genetic Interactions

Statement

Reference

Flies carrying both phyl^hs.sev and ttk^{88.hs.sev.T:Hsap\MYC} have more normal eyes than flies carrying either phyl^hs.sev or ttk^{88.hs.sev.T:Hsap\MYC} alone.

(Tang et al., 1997)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

5776

P{sev-ttk88}AT1

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

ttk^{88.hs.sev.T:Hsap\MYC}

ttk^{88.hs.sev.T:Myc}

ttk^{88.hs.sev.Tag:MYC}

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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