FlyBase Allele Report: Dmel\pav[S093413]

General Information

Symbol

Dmel\pav^S093413

Species

D. melanogaster

Name

FlyBase ID

FBal0082376

Feature type

allele

Associated gene

Dmel\pav

Associated Insertion(s)

P{lacW}pav^S093413

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Delta2-3 transposase

(Deak et al., 1997)

P-element activity

(Szeged Stock Center, 1998-, Salzberg et al., 1997)

Progenitor genotype

Associated Insertion(s)

P{lacW}pav^S093413

Cytology

Description

Insertion of a P{lacW} element 191bp upstream of the first ATG codon of the pav open reading frame.

(Adams et al., 1998)

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3L:4,242,687..4,242,687 [+]

(Adams et al., 1998, Szeged Stock Center, 1998-, Deak et al., 1997, Salzberg et al., 1997)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

mitotic domain 1 | embryonic cycle 16

(Adams et al., 1998)

neuron | embryonic stage

(Salzberg et al., 1997)

presumptive embryonic/larval peripheral nervous system

(Salzberg et al., 1997)

Detailed Description

Statement

Reference

Homozygous or hemizygous embryos show cytokinesis defects during mitosis 16.

(Adams et al., 1998)

Early lethal.

(Deak et al., 1997)

In the absence of pav cell division in the PNS is impaired and cells that fail to divide grow in size. Embryos exhibit reduced number of neurons in the PNS, remaining cells are enlarged.

(Salzberg et al., 1997)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Δ2-3 induced reversion demonstrates the insertion is responsible for the lethal phenotype.

(Salzberg et al., 1997)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

0934/13

(Deak et al., 1997)

934/13

(Salzberg et al., 1997)

pav^934/13

(Adams et al., 1998)

pav^S093413

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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