FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\E(Pc)2
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General Information
Symbol
Dmel\E(Pc)2
Species
D. melanogaster
Name
FlyBase ID
FBal0086003
Feature type
allele
Associated gene
Dmel\E(Pc)
Associated Insertion(s)
P{wen.4}E(Pc)2
Carried in Construct
Also Known As
4-12E
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Sinclair et al., 1998, Kassis, 1994)
Progenitor genotype
Associated Insertion(s)
P{wen.4}E(Pc)2
Cytology
Description

Insertion of a P-element.

(Stankunas et al., 1998)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Dominantly suppresses position effect variegation (PEV) at the w locus caused by In(1)wm4, PEV at the B locus caused by Dp(1;Y)BSCV, PEV at the Sb locus caused by T(2;3)SbV and PEV at the bw locus caused by In(2R)bwVDe2.

      (Sinclair et al., 1998)

      Enhances the homeotic phenotype of Pcunspecified. Suppresses position effect variegation caused by In(1)wm4 and T(2;3)SbV.

      (Stankunas et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      E(Pc)2 is an enhancer of visible | dominant phenotype of Pc4

      (Sinclair et al., 1998)
      Other
      Statement
      Reference

      E(Pc)2, ash122 has visible | dominant | homeotic phenotype

      (Gildea et al., 2000)

      E(Pc)[+]/E(Pc)2, ash122 has visible | dominant | homeotic phenotype

      (Gildea et al., 2000)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      E(Pc)2 is an enhancer of leg phenotype of Pc4

      (Sinclair et al., 1998)

      E(Pc)[+]/E(Pc)2 is an enhancer of sex comb | ectopic phenotype of Pc4

      (Sinclair et al., 1998)

      E(Pc)2 is an enhancer of phenotype of Pcunspecified

      (Stankunas et al., 1998)
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Dominantly enhances the extra sex combs phenotype of Pc4.

      (Sinclair et al., 1998)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      4-12E
      (Sinclair et al., 1998, Kassis, 1994)
      E(Pc)2
      Name Synonyms
      Secondary FlyBase IDs
        References (4)