FlyBase Allele Report: Dmel\en[unspecified]

General Information

Symbol

Dmel\en^unspecified

Species

D. melanogaster

Name

FlyBase ID

FBal0086643

Feature type

allele

Associated gene

Dmel\en

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

(FlyBase Curators, 2025-)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die during embryonic stage | recessive

(Tearle and Nusslein-Volhard, 1987)

pair rule phenotype

(Tearle and Nusslein-Volhard, 1987)

pair rule phenotype | embryonic stage | recessive

(Tearle and Nusslein-Volhard, 1987)

some die during embryonic stage | recessive

(Tearle and Nusslein-Volhard, 1987)

viable (with en^{enHSP3.-250bp})

(Kwon et al., 2009)

Phenotype Manifest In

abdominal segment 6

(Tearle and Nusslein-Volhard, 1987)

abdominal segment 8

(Tearle and Nusslein-Volhard, 1987)

embryonic abdominal segment 2

(Tearle and Nusslein-Volhard, 1987)

embryonic abdominal segment 4

(Tearle and Nusslein-Volhard, 1987)

embryonic metathoracic segment

(Tearle and Nusslein-Volhard, 1987)

embryonic prothoracic segment

(Tearle and Nusslein-Volhard, 1987)

wing (with en^{enHSP3.-250bp})

(Kwon et al., 2009)

Detailed Description

Statement

Reference

Expression of UAS-en under the control of Scer\GAL4^en-e16E can cause posterior to anterior transformations of distal wing and notum structures.

(Baonza et al., 2000)

The anterior margin of each segment is defective in en^unspecified mutant embryos. There are pair rule defects in the naked cuticle of segments T1, T3, A2, A4, A6 and A8.

(Tearle and Nusslein-Volhard, 1987)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Other

Statement

Reference

en^unspecified, inv^unspecified has larval RP2 motor neuron | ectopic phenotype

(Bhat et al., 2000)

en^unspecified, inv^unspecified has RP2sib neuron | ectopic phenotype

(Bhat et al., 2000)

en^unspecified, wg^unspecified has embryonic epidermis phenotype

(Gritzan et al., 1999)

en^unspecified, wg^unspecified has ventral denticle belt phenotype

(Gritzan et al., 1999)

Additional Comments

Genetic Interactions

Statement

Reference

The RP2 lineage is duplicated in en^unspecified inv^unspecified embryos. The missing RP2 lineage phenotype of Df(2L)slp-Δ34B embryos is unaffected if the embryos are also carrying en^unspecified and inv^unspecified.

(Bhat et al., 2000)

Embryos null for both wg and en have no smooth cuticle, and the remaining denticles are row 5 like.

(Gritzan et al., 1999)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

en^unspecified

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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