FlyBase Allele Report: Mmus\Ctnnb1[UAS.cWa]

General Information

Symbol

Mmus\Ctnnb1^UAS.cWa

Species

M. musculus

Name

Saccharomyces cerevisiae UAS construct a of White

FlyBase ID

FBal0086801

Feature type

allele

Associated gene

Mmus\Ctnnb1

Associated Insertion(s)

Carried in Construct

P{UAS-Mmus\Ctnnb1.W}

Transgenic product class

cDNA

(White et al., 1998)

wild_type

(White et al., 1998)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(White et al., 1998)

wild_type

(White et al., 1998)

Mutagen

in vitro construct

(White et al., 1998)

Progenitor genotype

Carried in construct

P{UAS-Mmus\Ctnnb1.W}

Cytology

Description

A Mmus\Ctnnb1 cDNA is expressed under the control of UASt regulatory sequences.

(White et al., 1998)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Mmus\Ctnnb1

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^Bx-MS1096

(White et al., 1998)

Phenotype Manifest In

embryonic/first instar larval cuticle | ventral, with Scer\GAL4^arm.PS

(White et al., 1998)

ventral denticle belt, with Scer\GAL4^arm.PS

(White et al., 1998)

wing, with Scer\GAL4^Bx-MS1096

(White et al., 1998)

wing sensillum, with Scer\GAL4^Bx-MS1096

(White et al., 1998)

wing vein, with Scer\GAL4^Bx-MS1096

(White et al., 1998)

Detailed Description

Statement

Reference

Overexpression of Mmus\Catnb^Scer\UAS.cWa under the control of Scer\GAL4^Bx-MS1096 results in ectopic wing vein formation and loss of both anterior and posterior margin bristles.

(White et al., 1998)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressor of

Statement

Reference

Scer\GAL4^arm.PS/Mmus\Ctnnb1^UAS.cWa is a suppressor of embryonic/first instar larval cuticle phenotype of arm²

(White et al., 1998)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Mmus\Catnb^Scer\UAS.cWa expressed under the control of Scer\GAL4^arm.PS partially rescues hemizygous arm² embryos derived from homozygous arm² female germline clones. Expression of Mmus\Catnb^Scer\UAS.cWa under the control of Scer\GAL4^arm.PS in arm²/+ embryos derived from homozygous arm² female germline clones leads to a weak segment polarity phenotype (extra denticles in naked cuticle regions).

(White et al., 1998)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

Mmus\Catnb^Scer\UAS.cWa

Mmus\Catnb^UAS.cWa

Mmus\Ctnnb1^Scer\UAS.cWa

Mmus\Ctnnb1^UAS.cWa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of White

(White et al., 1998)

Secondary FlyBase IDs

References (1)

Report Sections

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