FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\CspE16
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General Information
Symbol
Dmel\CspE16
Species
D. melanogaster
Name
FlyBase ID
FBal0086885
Feature type
allele
Associated gene
Dmel\Csp
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
    Nature of the Allele
    Allele class

    loss of function allele

    (Ranjan et al., 1998)
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Synaptic boutons of homozygous neuromuscular junctions labelled with the dye FM1-43 fail to destain at 32oC after K+ depolarisation, in contrast to wild-type, and FM1-43 dye uptake cannot be evoked by K+ stimulation at 32oC. Destaining at 32oC is stimulated by black widow spider venom and calcimycin. Endocytotic uptake of FM1-43 at 32oC is stimulated by black widow spider venom.

        (Ranjan et al., 1998)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        CspE16
        cspE16
        (Ranjan et al., 1998)
        Name Synonyms
        Secondary FlyBase IDs
          References (1)