FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\spi::vnEGF.UAS
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General Information
Symbol
Dmel\spi::vnEGF.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0088611
Feature type
allele
Associated gene
spi::vn
Associated Insertion(s)
Carried in Construct
P{UAS-vn-spi.EGF}
Also Known As
Vn::Spi-EGF
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Schnepp et al., 1998)
Progenitor genotype
Carried in construct
P{UAS-vn-spi.EGF}
Cytology
Description

vn cDNA lacking the EGF motif, a type 1 cDNA corresponding to nucleotides 1679-3980, is fused with fragment encoding the spi EGF motif.

(Schnepp et al., 1998)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
spi::vn
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of spi::vnEGF.Scer\UAS under the control of Scer\GAL4cb41 in follicle cell clones results in border cell misguidance.

      (McDonald et al., 2006)

      Expression of spi::vnEGF.Scer\UAS under the control of Scer\GAL4bs-1348 results in extra veins in the wing.

      (Donaldson et al., 2004)

      Scer\GAL4bs-1348-mediated expression causes a strong extra-vein phenotype. Scer\GAL4GMR.PF-mediated expression causes small disorganised eyes with blisters.

      (Schnepp et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of spi::vnEGF.Scer\UAS under the control of Scer\GAL4vn.GAL4 rescues the lethality of vnL6/vnGAL4 mutants to the pharate adult stage.

      (Austin et al., 2014)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      spi::vnEGF.Scer\UAS
      spi::vnEGF.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (4)