FB2026_02 , released June 18, 2026
Allele: Dmel\quaWP614
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General Information
Symbol
Dmel\quaWP614
Species
D. melanogaster
Name
FlyBase ID
FBal0088678
Feature type
allele
Associated gene
Dmel\qua
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In

        nurse cell & actin filament

        (Matova et al., 1999)
        Detailed Description
        Statement
        Reference

        Female flies show a gradual reduction in fertility as they are moved from 18oC to 22oC to 29oC. At 22oC, stage 10B egg chambers contain abundant actin bundles that are shorter than normal.

        (Matova et al., 1999)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        NOT suppressed by
        Statement
        Reference

        quaWP614 has female sterile phenotype, non-suppressible by Hsap\VIL1Germ.PM

        (Matova et al., 1999)
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference

        quaWP614 females expressing Hsap\VILGerm.PM at 22oC are completely sterile, in contrast to quaWP614 females, which are moderately fertile at this temperature. The quaWP614 phenotype is not altered by the expression of Hsap\VILGerm.PM, and later in oogenesis the nurse cells of quaWP614 females expressing Hsap\VILGerm.PM contain few if any actin bundles and transport is severely disrupted.

        (Matova et al., 1999)
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        quaWP614
        Name Synonyms
        Secondary FlyBase IDs
          References (2)