FlyBase Allele Report: Dmel\mew[unspecified]

General Information

Symbol

Dmel\mew^unspecified

Species

D. melanogaster

Name

FlyBase ID

FBal0088812

Feature type

allele

Associated gene

Dmel\mew

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

(FlyBase Curators, 2025-)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

mew[+]/mew^unspecified is a non-enhancer of abnormal neuroanatomy | embryonic stage phenotype of Scer\GAL4^P52, Sema1a^UAS.cYa, Sema1a^k13702

(Cho et al., 2012)

NOT Suppressor of

Statement

Reference

mew[+]/mew^unspecified is a non-suppressor of abnormal neuroanatomy | embryonic stage phenotype of Scer\GAL4^P52, Sema1a^UAS.cYa, Sema1a^k13702

(Cho et al., 2012)

Phenotype Manifest In

Enhancer of

Statement

Reference

mew^unspecified is an enhancer of muscle attachment site & basal lamina phenotype of if^B4

(Prokop et al., 1998)

NOT Enhancer of

Statement

Reference

mew[+]/mew^unspecified is a non-enhancer of larval posterior commissure | embryonic stage phenotype of Scer\GAL4^P52, Sema1a^UAS.cYa, Sema1a^k13702

(Cho et al., 2012)

NOT Suppressor of

Statement

Reference

mew[+]/mew^unspecified is a non-suppressor of larval posterior commissure | embryonic stage phenotype of Scer\GAL4^P52, Sema1a^UAS.cYa, Sema1a^k13702

(Cho et al., 2012)

Other

Statement

Reference

if^B4, mew^unspecified has muscle attachment site phenotype

(Prokop et al., 1998)

Additional Comments

Genetic Interactions

Statement

Reference

The commissural axon phenotype (failure to cross the midline) seen in embryos expressing Sema-1a^Scer\UAS.cYa under the control of Scer\GAL4^P52 in a Sema-1a^k13702 null background is not affected if the embryos are also heterozygous for mew^unspecified.

(Cho et al., 2012)

if^B4 mew^unspecified double mutant embryos have a more severe muscle detachment phenotype than if^B4 single mutant embryos. The basement membrane detaches or fails to assemble in epidermal HAJs in these embryos.

(Prokop et al., 1998)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

mew^unspecified

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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