FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\escTag:HA
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General Information
Symbol
Dmel\escTag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0089291
Feature type
allele
Associated gene
Dmel\esc
Associated Insertion(s)
Carried in Construct
P{HA-esc}
Also Known As
HA-ESC
Key Links
Transgenic product class
genomic_DNA
(Jones et al., 1998)
wild_type
(Jones et al., 1998)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Jones et al., 1998)
wild_type
(Jones et al., 1998)
Mutagen
in vitro construct
(Jones et al., 1998)
Progenitor genotype
Carried in construct
P{HA-esc}
Cytology
Description

1.1kb PstI fragment carrying haemagglutinin (HA) epitope tagged genomic copy of esc (4.2kb XbaI fragment), tag located 3bp upstream of the ATG.

(Jones et al., 1998)
Allele components
Component
Use(s)
Regulatory region(s)
esc
Encoded product / tool
esc
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      escTag:HA rescues escunspecified

      (Jones et al., 1998)
      Comments

      Rescue of lethality and restoration of normal homeotic gene expression.

      (Jones et al., 1998)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Expressed in embryos and extracts tested for coimmunoprecipitation to E(z) antibodies and presence of E(z) association with esc in vivo. Also used in GST pull-down assays to study interaction of E(z) immobilised on the beads and esc from embryo extracts.

      (Jones et al., 1998)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      esc+t4.2.T:HA1
      esc+t4.2.T:Ivir\HA1
      escT:Ivir\HA1
      escTag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (5)