FlyBase Allele Report: Dmel\eya[E(P)10]

General Information

Symbol

Dmel\eya^E(P)10

Species

D. melanogaster

Name

FlyBase ID

FBal0089395

Feature type

allele

Associated gene

Dmel\eya

Associated Insertion(s)

Carried in Construct

Also Known As

Df(2L)eya

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal size | adult stage (with eya^cs)

(Tian et al., 2019)

lethal - all die during embryonic stage (with eya^E1)

(Bui et al., 2000)

lethal - all die during embryonic stage (with eya^E4)

(Bui et al., 2000)

lethal - all die during embryonic stage (with eya^E7)

(Bui et al., 2000)

lethal - all die during embryonic stage (with eya^E8)

(Bui et al., 2000)

lethal - all die during embryonic stage (with eya^E11)

(Bui et al., 2000)

lethal - all die during embryonic stage (with eya^E12)

(Bui et al., 2000)

lethal - all die during embryonic stage | partially (with eya^IR1)

(Bui et al., 2000)

some die during embryonic stage (with eya^E1)

(Bui et al., 2000)

some die during embryonic stage (with eya^E4)

(Bui et al., 2000)

some die during embryonic stage (with eya^E7)

(Bui et al., 2000)

some die during embryonic stage (with eya^E8)

(Bui et al., 2000)

some die during embryonic stage (with eya^E11)

(Bui et al., 2000)

some die during embryonic stage (with eya^E12)

(Bui et al., 2000)

some die during embryonic stage | partially (with eya^IR1)

(Bui et al., 2000)

visible (with eya¹)

(Bui et al., 2000)

visible | adult stage (with eya^cs)

(Tian et al., 2019)

Phenotype Manifest In

cephalopharyngeal skeleton

(Bonini et al., 1998)

eye (with eya¹)

(Bui et al., 2000)

eye (with eya^cs)

(Tian et al., 2019)

germarium (with eya³)

(Bai and Montell, 2002)

germline cell (with eya³)

(Bai and Montell, 2002)

ventral denticle belt

(Bonini et al., 1998)

Detailed Description

Statement

Reference

eya^2m23a/eya^E(P)10 adults exhibit eyes similar to controls.

eya^cs/eya^E(P)10 adults exhibit less severe eye phenotypes than eya^cs/eya², eya^cs/eya¹, eya^cs/In(2LR)ETD2.2 and eya^cs/eya^cs adults.

(Tian et al., 2019)

eya³/eya^E(P)10 have egg chambers which contain abnormal germline cells. In extreme cases, ovarian development ceases in the germarium and the germarium appears swollen compared to wild type.

(Bai and Montell, 2002)

eya¹/eya^E(P)10 flies are eyeless. More than 50% of eya^E1/eya^E(P)10, eya^E4/eya^E(P)10, eya^E7/eya^E(P)10, eya^E8/eya^E(P)10, eya^E11/eya^E(P)10 or eya^E12/eya^E(P)10 animals die as embryos. Less than 50% of eya^IR1/eya^E(P)10 animals die as embryos.

(Bui et al., 2000)

The setal belts are often condensed in eya^D1/eya^E(P)10 embryos and the cephalopharyngeal skeleton is broad, fused and distorted.

(Bonini et al., 1998)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

eya^E11.Scer\UAS shows a synergy in ectopic eye formation when coexpressed under the control of Scer\GAL4^dpp.blk1 with dac^Scer\UAS.cSa.

(Bui et al., 2000)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Df(2L)eya

(Tian et al., 2019, Bui et al., 2000)

E(P)10

(Bai and Montell, 2002)

cli^E(P)10

eya^E(P)10

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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