FlyBase Allele Report: Dmel\Khc[unspecified]

General Information

Symbol

Dmel\Khc^unspecified

Species

D. melanogaster

Name

FlyBase ID

FBal0089618

Feature type

allele

Associated gene

Dmel\Khc

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

(FlyBase Curators, 2025-)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal locomotor behavior | larval stage

(Füger et al., 2012)

lethal | recessive

(Liu et al., 1999)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Khc[+]/Khc^unspecified is an enhancer of partially lethal phenotype of ens^ΔC

(Sung et al., 2008)

Other

Statement

Reference

Dhc64C^4-19, Khc[+]/Khc^unspecified has paralytic | dominant | larval stage phenotype

(Martin et al., 1999)

Khc[+]/Khc^unspecified, Klc^unspecified has paralytic | dominant | larval stage phenotype

(Martin et al., 1999)

Dhc64C[+]/Dhc64C^4-19, Khc^unspecified has paralytic | dominant | larval stage phenotype

(Martin et al., 1999)

Khc^unspecified, Klc^unspecified/Klc[+] has paralytic | dominant | larval stage phenotype

(Martin et al., 1999)

Phenotype Manifest In

Enhanced by

Statement

Reference

Khc^unspecified has phenotype, enhanceable by Dhc64C[+]/Dhc64C^ek1

(Martin et al., 1997)

Other

Statement

Reference

Dhc64C^4-19, Khc[+]/Khc^unspecified has posterior fascicle & axon phenotype

(Martin et al., 1999)

Khc[+]/Khc^unspecified, Klc^unspecified has posterior fascicle & axon phenotype

(Martin et al., 1999)

Dhc64C[+]/Dhc64C^4-19, Khc^unspecified has posterior fascicle & axon phenotype

(Martin et al., 1999)

Khc^unspecified, Klc^unspecified/Klc[+] has posterior fascicle & axon phenotype

(Martin et al., 1999)

Additional Comments

Genetic Interactions

Statement

Reference

Dhc64C^4-19 Khc^unspecified double heterozygous larvae show a posterior paralysis phenotype. Axon swellings are seen. Khc^unspecified Klc^unspecified double heterozygous larvae show a posterior paralysis phenotype. Axon swellings are seen.

(Martin et al., 1999)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Khc^unspecified is rescued by Khc^{Ubi-p63E.Tag:MYC}

(Brendza et al., 1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Khc^unspecified

l(2)W12^unspecified

Name Synonyms

Secondary FlyBase IDs

FBal0101328

References (8)

Report Sections

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