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General Information
Symbol
Dmel\tinUAS.cYa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Yin
FlyBase ID
FBal0090094
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-tin
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

A tin cDNA is expressed under the control of UASt regulatory sequences.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of tinScer\UAS.cYa in the dorsal mesoderm in stage 11-12 embryos, driven by Scer\GAL4tin.cBa, does not induce the production of supernumerary cardioblasts.

Ectopic expression of tinScer\UAS.cYa in the lateral domain of the cardiogenic mesoderm, driven by either Scer\GAL4Mef2.PR or Scer\GAL4twi.PG, causes a marked reduction of lymph-gland progenitors and pericardial cells in stage 16 embryos.

When tinScer\UAS.cYa is expressed under the control of Scer\GAL4twi.PB the embryonic dorsal vessel is either distorted or does not form at all.

Stage 11 embryos expressing tinScer\UAS.cYa under the control of both Scer\GAL4how-24B and Scer\GAL4twi.PG have enlarged clusters of pericardial cell progenitors; each cluster contains 6-10 eve-expressing cells (e-PCs) compared to 3-4 cells per cluster in wild-type embryos. The number of e-PCs decreases to a normal level during subsequent stages and the heart appears to be normal.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Expression of tinScer\UAS.cYa, driven by Scer\GAL4tin.cBa, results in the rescue of few additional cardioblasts in a Df(3L)DocA background. Coexpression of pnrScer\UAS.cHa and tinScer\UAS.cYa, under the control of Scer\GAL4tin.cBa, induces the formation of more cardioblasts than expression of pnrScer\UAS.cHa alone. When Doc2Scer\UAS.cRa is coexpressed with only tinScer\UAS.cYa, or pnrScer\UAS.cHa and tinScer\UAS.cYa together, large numbers of extra cardioblasts are formed. Expression of all three transgenes results in double the amount of cardioblasts compared to wild type. Coexpression of Doc2Scer\UAS.cRa, tinScer\UAS.cYa, and pnrScer\UAS.cHa, under the control of Scer\GAL4twi.2PE, causes widespread ectopic cardioblast formation to a much greater extent than expression of Doc2Scer\UAS.cRa alone or in combination with tinScer\UAS.cYa plus pnrScer\UAS.cHa.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
tinScer\UAS.cYa
tinUAS.cYa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Yin
Secondary FlyBase IDs
    References (13)