FB2026_02 , released June 18, 2026
Allele: Dmel\cswSH2SH2.hs.2sev
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General Information
Symbol
Dmel\cswSH2SH2.hs.2sev
Species
D. melanogaster
Name
FlyBase ID
FBal0090452
Feature type
allele
Associated gene
Dmel\csw
Associated Insertion(s)
Carried in Construct
P{SE-cswSH2SH2}
Key Links
Transgenic product class
inframe_deletion
(Allard et al., 1998)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Allard et al., 1998)
Mutagen
in vitro construct
(Allard et al., 1998)
Progenitor genotype
Carried in construct
P{SE-cswSH2SH2}
Cytology
Description

sev enhancers and an Hsp70 promoter drive expression of the SH2 domains (amino acids 1 to 231) of csw.

(Allard et al., 1998)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
sev
Encoded product / tool
csw
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies expressing cswSH2SH2.hs.2sev in a wild-type background have rough eyes and have an R7 photoreceptor cell in less than 1% of ommatidia.

      (Allard et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      cswSH2SH2.hs.2sev fails to rescue csw13-87

      (Allard et al., 1998)

      cswSH2SH2.hs.2sev fails to rescue cswG547E.hs.2sev

      (Allard et al., 1998)
      Comments

      Does not rescue the zygotic lethality of csw13-87/Y males.

      (Allard et al., 1998)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      cswSH2SH2.hs.2sev
      Name Synonyms
      Secondary FlyBase IDs
        References (1)