FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Med7
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General Information
Symbol
Dmel\Med7
Species
D. melanogaster
Name
FlyBase ID
FBal0090584
Feature type
allele
Associated gene
Dmel\Med
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Wisotzkey et al., 1998)
Progenitor genotype
Cytology
Description

Amino acid replacement: C99S.

(Wisotzkey et al., 1998)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:31,612,209..31,612,209 [+]
Nucleotide change:

T31612209A

Amino acid change:

C99S | Med-PA; C99S | Med-PB; C99S | Med-PC

Reported amino acid change:

C99S

Comment:

The nucleotide position of the Cys to Ser mutation is ambiguous. It could be a TGC to AGC or TGC to TCC codon change. The codon change was not specified in FBrf0167516. Site of nucleic acid difference in mutant inferred by FlyBase based on reported amino acid change.

(Wisotzkey et al., 1998)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Med7 is an enhancer of wing vein phenotype of dpps6/dpphr4

      (Takaesu et al., 2005)

      Med7 is an enhancer of wing vein L5 phenotype of dpps6/dpphr4

      (Takaesu et al., 2005)

      Med7 is an enhancer of wing vein L4 phenotype of dpps6/dpphr4

      (Takaesu et al., 2005)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      dpps6/dpphr4 Med7 flies exhibit L4 and L5 wing vein defects in approximately 42% of cases, with 15% of these wings also exhibiting defects in L2, or the posterior crossvein or margin notches.

      (Takaesu et al., 2005)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Med7
      (Quijano et al., 2011, Takaesu et al., 2005)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)