FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\tkvDE-Q199D.tld.Tag:HA
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General Information
Symbol
Dmel\tkvDE-Q199D.tld.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0092481
Feature type
allele
Associated gene
Dmel\tkv
Associated Insertion(s)
Carried in Construct
P{tld-tkv.DE-Q199D.T:HA1}
Key Links
Transgenic product class
inframe_deletion
(Haerry et al., 1998)
missense_variant
(Haerry et al., 1998)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Haerry et al., 1998)
missense_variant
(Haerry et al., 1998)
Mutagen
in vitro construct
(Haerry et al., 1998)
Progenitor genotype
Carried in construct
P{tld-tkv.DE-Q199D.T:HA1}
Cytology
Description

A 0.5kb fragment of the tld upstream region drives expression of tkv which lacks the extracellular domain, carries the amino acid replacement Q199D and is tagged with Tag:HA.

(Haerry et al., 1998)
Allele components
Component
Use(s)
Regulatory region(s)
tld
Encoded product / tool
tkv
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies expressing tkvDE-Q199D.tld.T:Ivir\HA1 under the control of Scer\GAL4A9 usually have no phenotype.

      (Haerry et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Flies expressing saxQ263D.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4A9 and also carrying tkvDE-Q199D.tld.T:Ivir\HA1 have blistered, darkly pigmented wings. Wings discs of these animals show overgrowth.

      (Haerry et al., 1998)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      tkvDE-Q199D.tld.T:HA1
      tkvDE-Q199D.tld.T:Ivir\HA1
      tkvDE-Q199D.tld.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)