FlyBase Allele Report: Dmel\caup[UAS.cdCa]

General Information

Symbol

Dmel\caup^UAS.cdCa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of del Corral

FlyBase ID

FBal0093133

Feature type

allele

Associated gene

Dmel\caup

Associated Insertion(s)

Carried in Construct

P{UAS-caup.dC}

Also Known As

UAS-caup

Key Links

Transgenic product class

wild_type

(Grillenzoni et al., 1998)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Grillenzoni et al., 1998)

Mutagen

in vitro construct

(Grillenzoni et al., 1998)

Progenitor genotype

Carried in construct

P{UAS-caup.dC}

Cytology

Description

UAS regulatory sequences drive caup expression.

(Grillenzoni et al., 1998)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

caup

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal planar polarity, with Scer\GAL4^Act5C.PI

(Cavodeassi et al., 1999)

visible, with Scer\GAL4^ey.PH

(Dominguez and de Celis, 1998)

visible, with Scer\GAL4^GMR.long

(Mazzoni et al., 2008)

Phenotype Manifest In

dorsal margin photoreceptor cell | ectopic, with Scer\GAL4^GMR.PF

(Tomlinson, 2003)

eye, with Scer\GAL4^Act5C.PI

(Cavodeassi et al., 1999)

eye, with Scer\GAL4^ey.PH

(Dominguez and de Celis, 1998)

eye, with Scer\GAL4^GMR.long

(Mazzoni et al., 2008)

eye | ectopic, with Scer\GAL4^Act5C.PI

(Cavodeassi et al., 1999)

ommatidium, with Scer\GAL4^Act5C.PI

(Cavodeassi et al., 1999)

scutum & microchaeta | medial, with Scer\GAL4^sca-537.4

(Grillenzoni et al., 1998)

vertical bristle, with Scer\GAL4^ey.PH

(Dominguez and de Celis, 1998)

Detailed Description

Statement

Reference

Expression of caup^{Scer\UAS.cdCa} under the control of Scer\GAL4^GMR.long leads to morphological defects in the eye.

(Mazzoni et al., 2008)

Misexpression of caup^{Scer\UAS.cdCa}, driven by Scer\GAL4^GMR.PF, in the ventral half of the eye allows the ectopic formation of dorsal rim ommatidia at the ventral extreme.

(Tomlinson, 2003)

Clones in the ventral region of the eye expressing caup^{Scer\UAS.cdCa} under the control of Scer\GAL4^Act5C.PI reorganise dorsoventral polarity and promoter formation of ectopic eye fields at a low frequency. Dorsally situated clones expressing caup^{Scer\UAS.cdCa} under the control of Scer\GAL4^Act5C.PI induce ectopic eyes at a low frequency.

(Cavodeassi et al., 1999)

When expression is driven by Scer\GAL4^ey.PH, the eye is very much reduced, and shows duplication of dorsal bristles.

(Dominguez and de Celis, 1998)

The medial macrochaetae of the notum have wild-type contralateral axonal branches in flies expressing caup^{Scer\UAS.cdCa} under the control of Scer\GAL4^sca-537.4. In contrast, the medial microchaetae of the notum lack all contralateral axonal branches in approximately 80% of these flies.

(Grillenzoni et al., 1998)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Scer\GAL4^GMR.long, ara^UAS.cGa, caup^UAS.cdCa has visible phenotype

(Mazzoni et al., 2008)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^ey.PH, caup^UAS.cdCa has eye phenotype, suppressible | partially by N^int.SH.UAS, Scer\GAL4^ey.PH

(Dominguez and de Celis, 1998)

Other

Statement

Reference

Scer\GAL4^GMR.long, ara^UAS.cGa, caup^UAS.cdCa has eye phenotype

(Mazzoni et al., 2008)

N^int.SH.UAS, Scer\GAL4^ey.PH, caup^UAS.cdCa has ommatidium phenotype

(Dominguez and de Celis, 1998)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of ara^Scer\UAS.cGa and caup^{Scer\UAS.cdCa} under the control of Scer\GAL4^GMR.long produces eye defects that are more severe than when either transgene is expressed alone.

(Mazzoni et al., 2008)

The eye-size effect in flies expressing caup^{Scer\UAS.cdCa} under the control of Scer\GAL4^ey.PH can be partially rescued by simultaneous expression of N^{int.SH.Scer\UAS}, though ommatidia are abnormally arranged.

(Dominguez and de Celis, 1998)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

R. del Corral J.L. Skarmeta J. Modolell

(Grillenzoni et al., 1998)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

caup^{Scer\UAS.cdCa}

caup^UAS.cdCa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of del Corral

(Grillenzoni et al., 1998)

Secondary FlyBase IDs

References (11)

Report Sections

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