FlyBase Allele Report: Dmel\B-H1[sev.PH]

General Information

Symbol

Dmel\B-H1^sev.PH

Species

D. melanogaster

Name

sevenless promoter construct of Hayashi

FlyBase ID

FBal0093523

Feature type

allele

Associated gene

Dmel\B-H1

Associated Insertion(s)

Carried in Construct

P{sev-B-H1.H}

Key Links

Transgenic product class

wild_type

(Hayashi et al., 1998)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Hayashi et al., 1998)

Mutagen

in vitro construct

(Hayashi et al., 1998)

Progenitor genotype

Carried in construct

P{sev-B-H1.H}

Cytology

Description

B-H1 is expressed under the control of a sev enhancer.

(Hayashi et al., 1998)

Allele components

Component

Use(s)

Regulatory region(s)

sev

Encoded product / tool

B-H1

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible

(Hayashi et al., 1998)

Phenotype Manifest In

Detailed Description

Statement

Reference

Flies carrying B-H1^sev.PH have rough eyes. Typical ommatidial defects include absence of 1-2 cone cells, 1-2 extra outer photoreceptors, loss of 1-2 endogenous outer photoreceptors, appearance of additional putative primary pigment cells partially similar in morphology to cone cells and the absence of photoreceptor R7. The total number of cell per ommatidium is normal and most if not all extra photoreceptor cells are transformants of anterior/posterior cone cell precursors. Cone cell precursors appear normal in late third instar larvae, but approximately half of pupal ommatidia lack 1-2 cone cells.

(Hayashi et al., 1998)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhanced by

Statement

Reference

B-H1^sev.PH has photoreceptor cell R1 | ectopic phenotype, enhanceable by aop^yan-1

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R2 | ectopic phenotype, enhanceable by aop^yan-1

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R5 | ectopic phenotype, enhanceable by Sos^JC2

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R6 | ectopic phenotype, enhanceable by Sos^JC2

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R1 phenotype, enhanceable by Ras85D^e2F

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R2 phenotype, enhanceable by Ras85D^e2F

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R3 phenotype, enhanceable by Ras85D^e2F

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R4 phenotype, enhanceable by Ras85D^e2F

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R5 phenotype, enhanceable by Ras85D^e2F

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R6 phenotype, enhanceable by Ras85D^e2F

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R3 | ectopic phenotype, enhanceable by aop^yan-1

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R4 | ectopic phenotype, enhanceable by aop^yan-1

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R5 | ectopic phenotype, enhanceable by aop^yan-1

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R6 | ectopic phenotype, enhanceable by aop^yan-1

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R1 | ectopic phenotype, enhanceable by Sos^JC2

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R2 | ectopic phenotype, enhanceable by Sos^JC2

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R3 | ectopic phenotype, enhanceable by Sos^JC2

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R4 | ectopic phenotype, enhanceable by Sos^JC2

(Hayashi et al., 1998)

Suppressed by

Statement

Reference

B-H1^sev.PH has photoreceptor cell R6 | ectopic phenotype, suppressible by Egfr^f11

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R1 | ectopic phenotype, suppressible by sev¹⁴

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R2 | ectopic phenotype, suppressible by sev¹⁴

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R3 | ectopic phenotype, suppressible by sev¹⁴

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R4 | ectopic phenotype, suppressible by sev¹⁴

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R5 | ectopic phenotype, suppressible by sev¹⁴

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R6 | ectopic phenotype, suppressible by sev¹⁴

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R1 | ectopic phenotype, suppressible by drk^e0A

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R2 | ectopic phenotype, suppressible by drk^e0A

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R3 | ectopic phenotype, suppressible by drk^e0A

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R4 | ectopic phenotype, suppressible by drk^e0A

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R5 | ectopic phenotype, suppressible by drk^e0A

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R6 | ectopic phenotype, suppressible by drk^e0A

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R1 | ectopic phenotype, suppressible by Sos^x122

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R2 | ectopic phenotype, suppressible by Sos^x122

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R3 | ectopic phenotype, suppressible by Sos^x122

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R4 | ectopic phenotype, suppressible by Sos^x122

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R5 | ectopic phenotype, suppressible by Sos^x122

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R6 | ectopic phenotype, suppressible by Sos^x122

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R1 | ectopic phenotype, suppressible by Ras85D^e2F

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R2 | ectopic phenotype, suppressible by Ras85D^e2F

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R3 | ectopic phenotype, suppressible by Ras85D^e2F

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R4 | ectopic phenotype, suppressible by Ras85D^e2F

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R5 | ectopic phenotype, suppressible by Ras85D^e2F

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R6 | ectopic phenotype, suppressible by Ras85D^e2F

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R1 | ectopic phenotype, suppressible by pnt^07825Δ78

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R2 | ectopic phenotype, suppressible by pnt^07825Δ78

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R3 | ectopic phenotype, suppressible by pnt^07825Δ78

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R4 | ectopic phenotype, suppressible by pnt^07825Δ78

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R5 | ectopic phenotype, suppressible by pnt^07825Δ78

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R6 | ectopic phenotype, suppressible by pnt^07825Δ78

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R1 | ectopic phenotype, suppressible by Raf¹

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R2 | ectopic phenotype, suppressible by Raf¹

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R3 | ectopic phenotype, suppressible by Raf¹

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R4 | ectopic phenotype, suppressible by Raf¹

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R5 | ectopic phenotype, suppressible by Raf¹

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R6 | ectopic phenotype, suppressible by Raf¹

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R1 | ectopic phenotype, suppressible by Egfr^f11

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R2 | ectopic phenotype, suppressible by Egfr^f11

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R3 | ectopic phenotype, suppressible by Egfr^f11

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R4 | ectopic phenotype, suppressible by Egfr^f11

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R5 | ectopic phenotype, suppressible by Egfr^f11

(Hayashi et al., 1998)

NOT suppressed by

Statement

Reference

B-H1^sev.PH has photoreceptor cell R7 phenotype, non-suppressible by Egfr^f11

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R7 phenotype, non-suppressible by drk^e0A

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R7 phenotype, non-suppressible by Sos^x122

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R7 phenotype, non-suppressible by pnt^07825Δ78

(Hayashi et al., 1998)

B-H1^sev.PH has photoreceptor cell R7 phenotype, non-suppressible by Raf¹

(Hayashi et al., 1998)

Suppressor of

Statement

Reference

B-H1^sev.PH is a suppressor of primary pigment cell phenotype of N^fa-g

(Hayashi et al., 1998)

Other

Statement

Reference

B-H1^sev.PH, aop^yan-1 has photoreceptor cell R7 | ectopic phenotype

(Hayashi et al., 1998)

B-H1^sev.PH, Sos^JC2 has photoreceptor cell R7 | ectopic phenotype

(Hayashi et al., 1998)

B-H1^sev.PH, N^fa-g has cone cell phenotype

(Hayashi et al., 1998)

Additional Comments

Genetic Interactions

Statement

Reference

Partially restores the formation of primary pigment cells in N^fa-g hemizygotes. The formation of these primary pigment cells is associated with cone cell loss. The extra outer photoreceptor phenotype caused by B-H1^sev.PH is significantly suppressed by Egfr^f11, sev¹⁴, drk^e0A, Sos^x122, Ras85D^e2F, phl¹ or pnt^07825Δ78. The fraction of B-H1^sev.PH ommatidia that lack 1 or 2 outer photoreceptors is increased by Ras85D^e2F. The loss of R7 cell phenotype caused by B-H1^sev.PH is unaffected by Egfr^f11, drk^e0A, Sos^x122, phl¹ or pnt^07825Δ78. The formation of extra outer photoreceptors caused by B-H1^sev.PH is enhanced by Sos^JC2 or aop^yan-1. Sos^JC2 or aop^yan-1 flies carrying B-H1^sev.PH have a considerable number of extra R7-like cells.

(Hayashi et al., 1998)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

B-H1^sev.PH

Name Synonyms

sevenless promoter construct of Hayashi

(Hayashi et al., 1998)

Secondary FlyBase IDs

References (1)

Report Sections

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