FlyBase Allele Report: Dmel\Rac2[GMR.PN]

General Information

Symbol

Dmel\Rac2^GMR.PN

Species

D. melanogaster

Name

glass multimer reporter construct of Nolan

FlyBase ID

FBal0094008

Feature type

allele

Associated gene

Dmel\Rac2

Associated Insertion(s)

Carried in Construct

P{GMR-Rac2.N}

Key Links

Transgenic product class

wild_type

(Nolan et al., 1998)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Nolan et al., 1998)

Mutagen

in vitro construct

(Nolan et al., 1998)

Progenitor genotype

Carried in construct

P{GMR-Rac2.N}

Cytology

Description

Full length coding region is expressed under the control of GMR regulatory sequences.

(Nolan et al., 1998)

Allele components

Component

Use(s)

Regulatory region(s)

GMR

engineered transcription regulatory region

Encoded product / tool

Rac2

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible

(Nolan et al., 1998)

Phenotype Manifest In

eye

(Nolan et al., 1998)

ommatidium

(Nolan et al., 1998)

photoreceptor

(Nolan et al., 1998)

pigment cell

(Nolan et al., 1998)

Detailed Description

Statement

Reference

Flies bearing one copy of P{GMR-Rac2.N} show a rough eye phenotype. Pigment cells are missing, ommatidial morphology is disrupted and photoreceptor cells are occasionally lost. Two copies of P{GMR-Rac2.N} increase the severity of the phenotype.

(Nolan et al., 1998)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressed by

Statement

Reference

Rac2^GMR.PN has eye phenotype, suppressible by mbc^2.35

(Nolan et al., 1998)

Rac2^GMR.PN has ommatidium phenotype, suppressible by mbc^2.35

(Nolan et al., 1998)

Rac2^GMR.PN has photoreceptor phenotype, suppressible by mbc^1.63

(Nolan et al., 1998)

Rac2^GMR.PN has pigment cell phenotype, suppressible by mbc^1.63

(Nolan et al., 1998)

Rac2^GMR.PN has eye phenotype, suppressible by mbc^4.25

(Nolan et al., 1998)

Rac2^GMR.PN has ommatidium phenotype, suppressible by mbc^4.25

(Nolan et al., 1998)

Rac2^GMR.PN has photoreceptor phenotype, suppressible by mbc^4.25

(Nolan et al., 1998)

Rac2^GMR.PN has pigment cell phenotype, suppressible by mbc^4.25

(Nolan et al., 1998)

Rac2^GMR.PN has photoreceptor phenotype, suppressible by mbc^2.35

(Nolan et al., 1998)

Rac2^GMR.PN has pigment cell phenotype, suppressible by mbc^2.35

(Nolan et al., 1998)

Rac2^GMR.PN has eye phenotype, suppressible by mbc^3.5

(Nolan et al., 1998)

Rac2^GMR.PN has ommatidium phenotype, suppressible by mbc^3.5

(Nolan et al., 1998)

Rac2^GMR.PN has photoreceptor phenotype, suppressible by mbc^3.5

(Nolan et al., 1998)

Rac2^GMR.PN has pigment cell phenotype, suppressible by mbc^3.5

(Nolan et al., 1998)

Rac2^GMR.PN has eye phenotype, suppressible by mbc^1.63

(Nolan et al., 1998)

Rac2^GMR.PN has ommatidium phenotype, suppressible by mbc^1.63

(Nolan et al., 1998)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Rac2^GMR.PN

Name Synonyms

glass multimer reporter construct of Nolan

(Nolan et al., 1998)

Secondary FlyBase IDs

References (1)

Report Sections

Open Close