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General Information
Symbol
Dmel\mbc4.25
Species
D. melanogaster
Name
FlyBase ID
FBal0093838
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Stage 15 embryos show unfused myoblasts. Dorsal closure is defective. mbc1.63/mbc4.25 embryos show a low penetrance defect in the fasciculation of axons in the ventral nerve cord. Some embryos show improper spacing between commissures and lack of fasciculation of ther longitudinal connectives.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressor of
Statement
Reference

mbc4.25 is a suppressor of eye phenotype of Rac1GMR.PN

mbc4.25 is a suppressor of ommatidium phenotype of Rac1GMR.PN

mbc4.25 is a suppressor of photoreceptor phenotype of Rac1GMR.PN

mbc4.25 is a suppressor of pigment cell phenotype of Rac1GMR.PN

mbc4.25 is a suppressor of eye phenotype of Rac2GMR.PN

mbc4.25 is a suppressor of ommatidium phenotype of Rac2GMR.PN

mbc4.25 is a suppressor of photoreceptor phenotype of Rac2GMR.PN

mbc4.25 is a suppressor of pigment cell phenotype of Rac2GMR.PN

NOT Suppressor of
Statement
Reference

mbc4.25 is a non-suppressor of eye phenotype of Rho1GMR.PH

mbc4.25 is a non-suppressor of eye phenotype of Cdc42GMR.PN

Additional Comments
Genetic Interactions
Statement
Reference

Dominantly suppresses the rough eye phenotye of Rac1GMR.PN and Rac2GMR.PN but has no effect on the eye phenotype of Cdc42GMR.PN or Rho1GMR.PH.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Su(rac)14.25
mbc4.25
Name Synonyms
Secondary FlyBase IDs
    References (1)