FB2026_03 , released September 17, 2026
Allele: Dmel\B52::tra2C.lacZ
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General Information
Symbol
Dmel\B52::tra2C.lacZ
Species
D. melanogaster
Name
FlyBase ID
FBal0094092
Feature type
allele
Associated gene
B52::tra2
Associated Insertion(s)
Carried in Construct
P{B52::tra2C.T:lacZ}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Dauwalder and Mattox, 1998)
Progenitor genotype
tra2C.lacZ
(Dauwalder and Mattox, 1998)
Carried in construct
P{B52::tra2C.T:lacZ}
Cytology
Description

The tra2 RS2 domain (amino acids 193 to 264) has been replaced by the B52 RS domain (amino acids 198 to 333).

(Dauwalder and Mattox, 1998)
Allele components
Component
Use(s)
Regulatory region(s)
tra2
Encoded product / tool
B52::tra2
Tagged with
lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      B52::tra2C.lacZ is a suppressor of abnormal sex-determination | recessive phenotype of tra2B

      (Dauwalder and Mattox, 1998)
      Other
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Partially rescues somatic sexual differentiation of XX tra2B flies, sometimes producing fully rescued female flies (female abdominal pigmentation, number of sixth sternite bristles, female genitalia and number of sex combs are rescued). Female fertility is rescued in some lines but not in others. Male fertility is not rescued.

      (Dauwalder and Mattox, 1998)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      B52::tra2C.T:Ecol\lacZ
      B52::tra2C.T:lacZ
      B52::tra2C.lacZ
      Name Synonyms
      Secondary FlyBase IDs
        References (1)