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General Information
Symbol
Dmel\wgPE6
Species
D. melanogaster
Name
FlyBase ID
FBal0094274
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Nucleotide change:

C7312877T

Reported nucleotide change:

C?T

Amino acid change:

A136V | wg-PA

Reported amino acid change:

A136V

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: A136V. Nucleotide substitution: C to T.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

When raised at 25oC both cluster I and II of the slou expressing muscle founder cells are reduced. At 18oC this phenotype is somewhat weaker, cluster II is more strongly affected than cluster I.

Temperature sensitive allele. Homozygous embryos raised at 25oC show more segmentation than wg loss of function mutants and produce denticle morphologies other than just row 5 type, but only at a low frequency. At 18oC, the pattern on the ventral surface of the cuticle is almost wild-type, but there is limited patterning of the dorsal surface.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Fails to complement
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
wgPE6
Name Synonyms
Secondary FlyBase IDs
    References (2)