FlyBase Allele Report: Dmel\babo[Np4]

General Information

Symbol

Dmel\babo^Np4

Species

D. melanogaster

Name

FlyBase ID

FBal0094578

Feature type

allele

Associated gene

Dmel\babo

Associated Insertion(s)

Carried in Construct

Also Known As

babo^Df

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Caused by aberration

Df(2R)Np4

Cytology

Description

Proximal break of Df(2R)Np4 falls in the ORF of babo in the exon 2-3a region.

(Brummel et al., 1999)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell number | larval stage (with babo⁴)

(Lee et al., 2024)

abnormal cell number | larval stage (with babo^AΔ7)

(Lee et al., 2024)

abnormal neuroanatomy | larval stage (with babo⁴)

(Lee et al., 2024)

abnormal neuroanatomy | larval stage (with babo^AΔ7)

(Lee et al., 2024)

abnormal size | larval stage (with babo⁴)

(Lee et al., 2024)

abnormal size | larval stage (with babo^CΔ1)

(Lee et al., 2024)

abnormal size | late third instar larval stage (with babo⁴)

(Peterson and O'Connor, 2013)

decreased body size | larval stage (with babo⁴)

(Lee et al., 2024)

decreased body size | larval stage (with babo^BΔ4)

(Lee et al., 2024)

decreased size | larval stage (with babo^AΔ7)

(Lee et al., 2024)

decreased size | pharate adult stage (with babo^AΔ7)

(Lee et al., 2024)

lethal - all die before end of larval stage (with babo⁴)

(Lee et al., 2024)

lethal - all die before end of P-stage (with babo^AΔ7)

(Lee et al., 2024)

lethal - all die before end of P-stage (with babo^BΔ4)

(Lee et al., 2024)

visible | P-stage (with babo^AΔ7)

(Lee et al., 2024)

Phenotype Manifest In

adult brain | pharate adult stage (with babo^AΔ7)

(Lee et al., 2024)

embryonic/larval anal pad | larval stage (with babo^CΔ1)

(Lee et al., 2024)

embryonic/larval optic lobe | larval stage (with babo⁴)

(Lee et al., 2024)

embryonic/larval optic lobe | larval stage (with babo^AΔ7)

(Lee et al., 2024)

eye photoreceptor cell | larval stage (with babo⁴)

(Lee et al., 2024)

eye photoreceptor cell | larval stage (with babo^AΔ7)

(Lee et al., 2024)

lamina forming neuroblast | larval stage (with babo⁴)

(Lee et al., 2024)

lamina forming neuroblast | larval stage (with babo^AΔ7)

(Lee et al., 2024)

larval brain (with babo⁴)

(Lee et al., 2024)

larval brain (with babo^AΔ7)

(Lee et al., 2024)

larval brain | late third instar larval stage (with babo⁴)

(Peterson and O'Connor, 2013)

larval central brain (with babo⁴)

(Lee et al., 2024)

larval central brain (with babo^AΔ7)

(Lee et al., 2024)

larval ventral nerve cord (with babo⁴)

(Lee et al., 2024)

larval ventral nerve cord (with babo^AΔ7)

(Lee et al., 2024)

neuroblast | larval stage (with babo⁴)

(Lee et al., 2024)

neuroblast | larval stage (with babo^AΔ7)

(Lee et al., 2024)

optic lobe neuroepithelial cell | decreased number (with babo⁴)

(Lee et al., 2024)

optic lobe neuroepithelial cell | decreased number (with babo^AΔ7)

(Lee et al., 2024)

pupa (with babo^AΔ7)

(Lee et al., 2024)

Detailed Description

Statement

Reference

babo^Np4/babo⁴ mutant larvae display hypotrophy of the central nervous system in late third instar larvae.

(Peterson and O'Connor, 2013)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

babo^Df

(Lee et al., 2025, Lee et al., 2024)

babo^Np4

babo^Δ

(Peterson and O'Connor, 2013)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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