FlyBase Aberration Report: Dmel\Df(2R)Np4

General Information

Symbol

Df(2R)Np4

Species

D. melanogaster

Name

FlyBase ID

FBab0002008

Feature type

chromosomal_deletion

Also Known As

Df5423

Computed Breakpoints include

44F11;45C1

Features within 44F11--45C1

Sequence coordinates

2R:8,953,183..8,955,109 [+] (Df(2R)Np4:bk1)

(Brummel et al., 1999)

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

In(2)G50

(Konev et al., 1994, Konev et al., 1991)

Mutagen

gamma ray

(Konev et al., 1991)

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Taylor et al., 1998, Zhang et al., 1996, Konev et al., 1994, Konev et al., 1991)

Breakpoints

44F8-44F9;45B8-45C1

(Konev et al., 1994)

44F11-45A1;45B8-45C1

(Zhang et al., 1996)

44F;45B

(Taylor et al., 1998)

Causes alleles

babo^Np4

(Peterson and O'Connor, 2013, Brummel et al., 1999)

Carries alleles

Transposon Insertions

Formalized genetic data

bk1 hits babo << l(2)45Bc << bk2 << l(2)45Cb

Genetic mapping information

Comments

Breakpoint 1 was mapped to a BalI-BalI restriction fragment. The position of the restriction fragment on the reference sequence was inferred by a FlyBase curator.

(Brummel et al., 1999)

Comments on Cytology

Ref: FBrf0054224.

(Zhang et al., 1996)

Left limit of break 1 from polytene analysis (FBrf0054224) Right limit of break 1 from inclusion of babo (FBrf0073600) Left limit of break 2 from inclusion of Pkn (FBrf0067338) Right limit of break 2 from polytene analysis (FBrf0073600)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

Partially deleted / disrupted

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

dap

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

DCTN2-p50

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Gγ1

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

l(2)44Fa

(Konev et al., 1994)

l(2)44Fb

(Konev et al., 1994)

l(2)44Fc

(Konev et al., 1994)

l(2)45Bc

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

l(2)45Cb

(Konev et al., 1994)

l(2)03659

(Spradling et al., 1999, Zhang et al., 1996, BDGP Project Members, 1994-1999)

l(2)03845

(BDGP Project Members, 1994-1999)

l(2)06424

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

l(2)k00313

(BDGP Project Members, 1994-1999)

l(2)k04512

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

l(2)k06006

(BDGP Project Members, 1994-1999)

l(2)k06021

(BDGP Project Members, 1994-1999)

l(2)k10103

(BDGP Project Members, 1994-1999)

l(2)k13412

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

l(2)k16529

(BDGP Project Members, 1994-1999)

l(2)s1976

(BDGP Project Members, 1994-1999)

lin

(Zheng et al., 2003)

Mmp2

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Myd88

(Kambris et al., 2003, Tauszig-Delamasure et al., 2002)

Pkn

(Spradling et al., 1999, Konev et al., 1994)

RyR

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

srg

(Konev et al., 1994)

wun

(Spradling et al., 1999, Zhang et al., 1996, BDGP Project Members, 1994-1999)

Molecular Data

Myd88

(Tauszig-Delamasure et al., 2002)

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (0)

If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
In these cases, there will be no "Export to Hitlist" button to the left.

Related Comments

Phenotypic Data

In combination with other aberrations

NOT in combination with other aberrations

Shows a weak and incompletely penetrant dominant wing hair phenotype.

(Taylor et al., 1998)

Stocks (3)

5423

108223

102086

CyO, Duox^Cy dpy^lv1 pr¹ cn² / Df(2R)Np4, bw¹

Notes on Origin

Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

The Df(2R)Np4 chromosome acts as a dominant weak suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion), but this is a false positive result (the suppressor is not within the bounds of the deficient region) because the region of the deficiency is covered by one or more nonsuppressing deficiencies.

(Mason et al., 2004)

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Df(2R)NP4

(Wang et al., 2019, Lee et al., 2003, Taylor et al., 1998)

Df(2R)Np4

Df(2R)Np⁴

(Konev et al., 1994)

Df5423

(Kambris et al., 2003, Tauszig-Delamasure et al., 2002)

Name Synonyms

Secondary FlyBase IDs

References (19)

Report Sections

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