FB2026_02 , released June 18, 2026
Allele: Dmel\wupA24597
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General Information
Symbol
Dmel\wupA24597
Species
D. melanogaster
Name
FlyBase ID
FBal0095141
Feature type
allele
Associated gene
Dmel\wupA
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
(Prado et al., 1999)
Progenitor genotype
Cytology
Description

Deletion of approximately 0.4kb in the region between exons 2 and 3.

(Prado et al., 1999)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      wupA24597 males die during embryogenesis and have hypodermal and neural phenotypes. wupA24597/+ females that do not survive die at the embryonic or first larval instar stages. Those that survive to eclosion (10-30%) have a reduced body size. The semi-dominant lethality of wupA24597 is not complemented by l(1)16Fe1 or the '23437' chromosome (in which l(1)16Fm and l(1)16Fe are affected).

      (Prado et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      wupA24597 has lethal | dominant phenotype, suppressible by Dp(1;3)JC153

      (Casas-Tintó and Ferrús, 2021)

      wupA24597 has lethal | dominant phenotype, suppressible by Dp(1;2)CH322-143G12

      (Casas-Tintó and Ferrús, 2021)
      NOT suppressed by
      Statement
      Reference

      wupA24597 has lethal | dominant phenotype, non-suppressible by Dp(1;2)CH322-61E2

      (Casas-Tintó and Ferrús, 2021)

      wupA24597 has lethal | dominant phenotype, non-suppressible by Dp(1;3)CH322-4P16

      (Casas-Tintó and Ferrús, 2021)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      24597SDL
      (Casas-Tintó and Ferrús, 2021)
      24597SDL
      (Prado et al., 1999)
      wupA24597
      Name Synonyms
      Secondary FlyBase IDs
        References (2)