FlyBase Allele Report: Dmel\SkpA[EP1423]

General Information

Symbol

Dmel\SkpA^EP1423

Species

D. melanogaster

Name

FlyBase ID

FBal0095199

Feature type

allele

Associated gene

Dmel\SkpA

Associated Insertion(s)

P{EP}SkpA^EP1423

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Wing et al., 2002, Gene Disruption Project members, 2001-, Murphy, 1999.3.10)

Progenitor genotype

Associated Insertion(s)

P{EP}SkpA^EP1423

Cytology

Description

P{EP} element located in the first intron of skpA.

(Murphy, 2003)

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

X:656,660..656,660 [+]

(Murphy, 2003, Wing et al., 2002, Gene Disruption Project members, 2001-, Murphy, 1999.3.10)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of SkpA^EP1423 under the control of Scer\GAL4^vg.PM does not result in an apparent wing phenotype.

(Colin et al., 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

SkpA^EP1423/Scer\GAL4^GMR.PF is an enhancer of visible phenotype of Scer\GAL4^GMR.PF, grim::rpr^rg.UAS

(Wing et al., 2002)

Suppressor of

Statement

Reference

SkpA^EP1423, Scer\GAL4^vg.PM is a suppressor of visible | adult stage phenotype of Mmus\Bax^UAS.cGa, Scer\GAL4^vg.PM

(Colin et al., 2014)

Other

Statement

Reference

Scer\GAL4^GMR.PF, SkpA^EP1423, grim::rpr^rg.UAS has partially lethal - majority die phenotype

(Wing et al., 2002)

Phenotype Manifest In

Enhancer of

Statement

Reference

SkpA^EP1423/Scer\GAL4^GMR.PF is an enhancer of eye phenotype of Scer\GAL4^GMR.PF, grim::rpr^rg.UAS

(Wing et al., 2002)

SkpA^EP1423/Scer\GAL4^GMR.PF is an enhancer of pigment cell phenotype of Scer\GAL4^GMR.PF, grim::rpr^rg.UAS

(Wing et al., 2002)

Suppressor of

Statement

Reference

SkpA^EP1423, Scer\GAL4^vg.PM is a suppressor of wing | adult stage phenotype of Mmus\Bax^UAS.cGa, Scer\GAL4^vg.PM

(Colin et al., 2014)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of skpA^EP1423 enhances the eye phenotype caused by expression of grim::rpr^rg.Scer\UAS under the control of Scer\GAL4^GMR.PF; eye size and/or pigmentation is reduced and the combination shows semi-lethality.

(Wing et al., 2002)

Xenogenetic Interactions

Statement

Reference

Co-expression of SkpA^EP1423 partially suppresses the notched wing phenotype observed in flies expressing Mmus\Bax^Scer\UAS.cGa under the control of Scer\GAL4^vg.PM.

(Colin et al., 2014)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

17222

w¹¹¹⁸ P{EP}SkpA^EP1423

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

SkpA^EP1423

skpA^EP1423

(Colin et al., 2014)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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