FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\l(3)S027714S027714
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General Information
Symbol
Dmel\l(3)S027714S027714
Species
D. melanogaster
Name
FlyBase ID
FBal0095301
Feature type
allele
Associated gene
l(3)S027714
Associated Insertion(s)
P{lacW}l(3)S027714S027714
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Deak et al., 1997)
P-element activity
(Szeged Stock Center, 1998-)
Progenitor genotype
Associated Insertion(s)
P{lacW}l(3)S027714S027714
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
AJ132809
AJ132813
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygotes die as first instar larvae.

      (Burmester et al., 2000)

      Lethality acts in the first larval instar.

      (Deak et al., 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      The location of the P{lacW}l(3)S027714S027714 insertion determined by Southern blotting using the plasmid rescue fragment is between Hsc70Cb and l(3)70Da. However, this location is in conflict with the complementation of the lethal phenotype of l(3)S027714S027714 by Df(3L)D-5rv6. The lethality of the "l(3)S027714" line can be reverted by excision of the P{lacW} element. Together these data suggest that the lethality of the "l(3)S027714" line not be caused by the P{lacW}l(3)S027714S027714 insertion but by some other, transposase sensitive, perhaps internally deleted P-element.

      (Burmester et al., 2000)
      Comments
      Comments

      Complements: l(3)j2E11j2E11.

      (Burmester et al., 2000)
      External Crossreferences and Linkouts ( 2 )
      Crossreferences
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      0277/14
      (Deak et al., 1997)
      l(3)S027714
      (Burmester et al., 2000)
      l(3)S027714S027714
      Name Synonyms
      Secondary FlyBase IDs
        References (4)