FB2026_02 , released June 18, 2026
Allele: Dmel\Su(rdgB)116116
Open Close
General Information
Symbol
Dmel\Su(rdgB)116116
Species
D. melanogaster
Name
FlyBase ID
FBal0095568
Feature type
allele
Associated gene
Su(rdgB)116
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Paetkau et al., 1999)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Heterozygotes show a retinal degeneration phenotype, showing light-enhanced deep pseudopupil loss. Rhabdomeres R1-R6 are small, very few rhabdomeres are missing and a few swollen cell bodies can be seen.

      (Paetkau et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Su(rdgB)116116 is a suppressor of retina phenotype of rdgB9

      (Paetkau et al., 1999)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Suppresses the retinal degeneration phenotype of rdgB9 flies; 50% of rdgB9; Su(rdgB)116116 flies retain a deep pseudopupil at days 5 and 21 under constant light and 12 hour light:dark conditions, respectively. 10 day old rdgB9; Su(rdgB)116116 flies raised in 12 hour light:dark conditions have uniformly smaller R1-R6 rhabdomeres than wild-type flies, but very few R1-R6 rhabdomeres or photoreceptors are missing, and the overall arrangement of the ommatidia is well intact. The electroretinogram light response amplitude of newly eclosed rdgB9 ; Su(rdgB)116116 flies is approximately 12mV (wild-type amplitude is 24mV).

      (Paetkau et al., 1999)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Selected as: Suppressor of the rdgB9 retinal degeneration phenotype.

      (Paetkau et al., 1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Su(rdgB)116
      (Paetkau et al., 1999)
      Su(rdgB)116116
      Name Synonyms
      Secondary FlyBase IDs
        References (1)