Construct: Gap1 deleted for the C2a, C2b, BTK, KYG and Q domains and the C-terminal portion of the PH domain is expressed from a sev enhancer/promoter cassette. Only the catalytic domain remains complete.
RasGAP1M.sev fails to rescue RasGAP1S1-11
RasGAP1M.sev fails to rescue RasGAP1B2