FlyBase Allele Report: Dmel\RasGAP1[S1-11]

General Information

Symbol

Dmel\RasGAP1^S1-11

Species

D. melanogaster

Name

FlyBase ID

FBal0042596

Feature type

allele

Associated gene

Dmel\RasGAP1

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

hypomorphic allele - genetic evidence

Mutagen

P-element activity

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Powe et al., 1999)

Mutagen

P-element activity

(Chang et al., 1995)

Progenitor genotype

RasGAP1^rI533

(Chang et al., 1995)

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

ommatidium

(Powe et al., 1999)

photoreceptor cell R7

(Powe et al., 1999, Chang et al., 1995)

Detailed Description

Statement

Reference

Average number of R7 cells per ommatidium is 2.5.

(Powe et al., 1999)

The phyl²³⁶⁶ mutation completely suppresses the supernumerary R7 phenotype of aop and Gap1 mutations.

(Chang et al., 1995)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

RasGAP1^S1-11 is rescued by RasGAP1^R786C.sev

(Powe et al., 1999)

RasGAP1^S1-11 is rescued by RasGAP1^sev.PP

(Powe et al., 1999)

Partially rescued by

RasGAP1^S1-11 is partially rescued by RasGAP1^ΔQ.sev

(Powe et al., 1999)

RasGAP1^S1-11 is partially rescued by RasGAP1^ΔN.sev

(Powe et al., 1999)

Not rescued by

RasGAP1^S1-11 is not rescued by RasGAP1^ΔC.sev

(Powe et al., 1999)

RasGAP1^S1-11 is not rescued by RasGAP1^ΔC2a.sev

(Powe et al., 1999)

RasGAP1^S1-11 is not rescued by RasGAP1^ΔBTK-Q.sev

(Powe et al., 1999)

RasGAP1^S1-11 is not rescued by RasGAP1^ΔC2b.sev

(Powe et al., 1999)

RasGAP1^S1-11 is not rescued by RasGAP1^M.sev

(Powe et al., 1999)

RasGAP1^S1-11 is not rescued by RasGAP1^ΔPH-Q.sev

(Powe et al., 1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Gap1^S1-11

RasGAP1^S1-11

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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