FB2026_03 , released September 17, 2026
Allele: Dmel\sv8
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General Information
Symbol
Dmel\sv8
Species
D. melanogaster
Name
FlyBase ID
FBal0096663
Feature type
allele
Associated gene
Dmel\sv
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Kavaler et al., 1999)
Mutagen
ethyl methanesulfonate
(Kavaler et al., 1999)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygotes are viable as late as the pharate adult stage. sv8/Df(4)G animals show embryonic lethality. Homozygotes can survive to the pharate adult stage and have profound bristle defects over the entire body surface. The bristle phenotypes closely resemble those of sv6 homozygotes. The microchaetae of the notum often have empty sockets. Macrochaetae also occasionally show a double socket phenotype. A mild roughening of the eye due to fusion of the ommatidia, and occasional scarring of the lens is seen. A somewhat higher fraction of sv8 homozygotes survive to the pharate adult stage than sv6 or sv7 homozygotes. Interacts very weakly with svspa-pol.

      (Kavaler et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      P29P29, sv8 has visible | dominant phenotype

      (Kavaler et al., 1999)
      Phenotype Manifest In
      Other
      Statement
      Reference

      P29P29, sv8 has adult abdomen & macrochaeta phenotype

      (Kavaler et al., 1999)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      P29P29; sv8 double heterozygotes show loss of bristles on the adult abdomen.

      (Kavaler et al., 1999)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Selected as: a mutation that produces loss of bristles on the adult abdomen in double heterozygous combination with P29P29.

      (Kavaler et al., 1999)
      Comments
      Comments

      The order of severity of the microchaete phenotype is: sv6 = sv7 = sv8 > svde > svn.

      (Kavaler et al., 1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      sv8
      Name Synonyms
      Secondary FlyBase IDs
        References (1)