FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Trf2G0039
Open Close
General Information
Symbol
Dmel\Trf2G0039
Species
D. melanogaster
Name
FlyBase ID
FBal0096851
Feature type
allele
Associated gene
Dmel\Trf2
Associated Insertion(s)
P{lacW}Trf2G0039
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Schäfer et al., 1999.3.29)
Progenitor genotype
Associated Insertion(s)
P{lacW}Trf2G0039
Cytology
Description

Maps to the second exon of Trf2.

(Bashirullah et al., 2007)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
AJ426773
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutants show defects in destruction of the larval salivary glands, having persistant larval salivary glands at the pupal stage.

      (Wang et al., 2008)

      Trf2G0039 animals die during the onset of metamorphosis. 85% of larvae pupariate, but 22% arrest development as prepupae and 63% die as pupae. The majority of pupae show defects in head eversion. Puparium are elongated and misshapen and pupae show defects in gas bubble translocation and anterior spiracle eversion.

      No Trf2G0039 embryonic lethality is observed.

      Trf2G0039 mutants have persistent larval salivary glands, and show defects in larval midgut cell death.

      (Bashirullah et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      Comments
      Comments

      P{lacW} not verified as causing the lethality.

      (Schäfer et al., 1999.3.29)
      External Crossreferences and Linkouts ( 1 )
      Crossreferences
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      TRF2G0039
      (Gibert and Karch, 2011)
      Trf2G0039
      dTrf2G0039
      (Bashirullah et al., 2007)
      l(1)G0039
      (Wang et al., 2008, Peter et al., 2002)
      l(1)G0039G0039
      (Popodi et al., 2010-)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)