FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Rsf1UAS.cLa
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General Information
Symbol
Dmel\Rsf1UAS.cLa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Labourier
FlyBase ID
FBal0097166
Feature type
allele
Associated gene
Dmel\Rsf1
Associated Insertion(s)
Carried in Construct
P{UAS-Rsf1.L}
Also Known As
UAS-RSF1
Key Links
Transgenic product class
cDNA
(Labourier et al., 1999)
wild_type
(Labourier et al., 1999)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Labourier et al., 1999)
wild_type
(Labourier et al., 1999)
Mutagen
in vitro construct
(Labourier et al., 1999)
Progenitor genotype
Carried in construct
P{UAS-Rsf1.L}
Cytology
Description

Wild-type Rsf1 cDNA is expressed under the control of UAS regulatory sequences.

(Labourier et al., 1999)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Rsf1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies expressing Rsf1Scer\UAS.cLa under the control of Scer\GAL4GMR.PF show retinal defects, the severity of which depends on the Rsf1Scer\UAS.cLa line used. Weak defects include a reduction in size of the eye, while more severe defects result in eyeless adults. Reduced viability is seen in some flies expressing Rsf1Scer\UAS.cLa under the control of Scer\GAL4GMR.PF, lethality increasing with the number of copies of Rsf1Scer\UAS.cLa. Flies expressing Rsf1Scer\UAS.cLa under the control of Scer\GAL4sca-537.4 show complete loss of bristles. Late pupal lethality is also seen when Rsf1Scer\UAS.cLa is expressed under the control of Scer\GAL4sca-537.4. Embryonic lethality is seen when Rsf1Scer\UAS.cLa is expressed under the control of Scer\GAL4da.G32.

      (Labourier et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      Suppressor of
      NOT Suppressor of
      Statement
      Reference

      Rsf1UAS.cLa, Scer\GAL4GMR.PF is a non-suppressor of retina phenotype of B52UAS.cKa, Scer\GAL4GMR.PF

      (Labourier et al., 1999)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Flies expressing both B52Scer\UAS.cKa and Rsf1Scer\UAS.cLa under the control of Scer\GAL4GMR.PF survive to adulthood and have retina defects. Flies expressing both B52Scer\UAS.cKa and Rsf1Scer\UAS.cLa under the control of Scer\GAL4sca-537.4 are viable and show complete (10% of flies) or partial (90% of flies) rescue of the sensory bristle pattern.

      (Labourier et al., 1999)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Rsf1Scer\UAS.cLa
      Rsf1UAS.cLa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Labourier
      (Labourier et al., 1999)
      Secondary FlyBase IDs
        References (3)