FB2026_03 , released September 17, 2026
Allele: Mmus\Gcm1UAS.cRa
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General Information
Symbol
Mmus\Gcm1UAS.cRa
Species
M. musculus
Name
Saccharomyces cerevisiae UAS construct a of Reifegerste
FlyBase ID
FBal0097222
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UASt regulatory sequences drive expression of the complete Mmus\Gcm1 open reading frame.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of Mmus\Gcm-rs1Scer\UAS.cRa under the control of Scer\GAL4sca-537.4 results in lethality. The extent of nerve cord condensation in these embryos is less than in age-matched wild-type embryos. Extra glial-like cells form at the expense of neurons in embryos expressing Mmus\Gcm-rs1Scer\UAS.cRa under the control of Scer\GAL4sca-537.4; there is a 60-80% reduction in the number of neurons per hemisegment and a similar increase in glial cells. The five neurons of the pentascolopidial lateral chordotonal organ (LCH5) are usually missing from abdominal segments, although they do occasionally form. Expression of Mmus\Gcm-rs1Scer\UAS.cRa under the control of Scer\GAL4arm.PS results in the formation of repo-expressing cells in the ectoderm which have the elongated and irregular shape typical of glial cells. The RP2 neurons are missing in 28% of hemisegments. The U/CQ neurons are occasionally missing and there is a minor reduction in the number of aCC/pCC neurons.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
Mmus\Gcm-rs1Scer\UAS.cRa
Mmus\Gcm1Scer\UAS.cRa
Mmus\Gcm1UAS.cRa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Reifegerste
Secondary FlyBase IDs
    References (1)