FlyBase Allele Report: Dmel\ppan[UAS.cMa]

General Information

Symbol

Dmel\ppan^UAS.cMa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Migeon

FlyBase ID

FBal0097923

Feature type

allele

Associated gene

Dmel\ppan

Associated Insertion(s)

Carried in Construct

P{UAS-ppan.M}

Key Links

Transgenic product class

cDNA

(Migeon et al., 1999)

wild_type

(Migeon et al., 1999)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Migeon et al., 1999)

wild_type

(Migeon et al., 1999)

Mutagen

in vitro construct

(Migeon et al., 1999)

Progenitor genotype

Carried in construct

P{UAS-ppan.M}

Cytology

Description

UASt regulatory sequences drive expression of a ppan cDNA.

(Migeon et al., 1999)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

ppan

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

increased cell death, with Scer\GAL4^en-e16E

(Migeon et al., 1999)

visible, with Scer\GAL4^Bx-MS1096

(Migeon et al., 1999)

visible, with Scer\GAL4^en-e16E

(Migeon et al., 1999)

Phenotype Manifest In

wing, with Scer\GAL4^Bx-MS1096

(Migeon et al., 1999)

wing, with Scer\GAL4^en-e16E

(Migeon et al., 1999)

wing | dorsal, with Scer\GAL4^Bx-MS1096

(Migeon et al., 1999)

wing | posterior, with Scer\GAL4^en-e16E

(Migeon et al., 1999)

wing disc, with Scer\GAL4^en-e16E

(Migeon et al., 1999)

wing hair & wing | dorsal, with Scer\GAL4^Bx-MS1096

(Migeon et al., 1999)

wing vein, with Scer\GAL4^en-e16E

(Migeon et al., 1999)

Detailed Description

Statement

Reference

Expression of ppan^Scer\UAS.cMa under the control of Scer\GAL4^en-e16E results in the posterior part of the wing having a crinkled appearance and increased opacity. Ectopic wing vein formation, thickening of wing veins and loss of wing veins is seen. Regions of wing imaginal discs expressing ppan^Scer\UAS.cMa under the control of Scer\GAL4^en-e16E show increased numbers of apoptotic cells. Flies in which one copy of ppan^Scer\UAS.cMa is expressed under the control of Scer\GAL4^Bx-MS1096 have wings which are slightly curved upward. There are fewer trichomes on the dorsal side of the wing than on the ventral side. In some spots on the dorsal side there are multiple fused trichomes, which probably come from single cells. Increasing the copy number of either ppan^Scer\UAS.cMa or Scer\GAL4^Bx-MS1096 ultimately results in near complete elimination of the wing.

(Migeon et al., 1999)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^Bx-MS1096, ppan^UAS.cMa has visible phenotype, suppressible by BacA\p35^UAS.cHa, Scer\GAL4^Bx-MS1096

(Migeon et al., 1999)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^Bx-MS1096, ppan^UAS.cMa has wing phenotype, suppressible by BacA\p35^UAS.cHa, Scer\GAL4^Bx-MS1096

(Migeon et al., 1999)

Additional Comments

Genetic Interactions

Statement

Reference

The wing phenotype caused by expression of ppan^Scer\UAS.cMa under the control of Scer\GAL4^Bx-MS1096 is rescued by co-expression of BacA\p35^Scer\UAS.cHa.

(Migeon et al., 1999)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

ppan^Scer\UAS.cMa

ppan^UAS.cMa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Migeon

(Migeon et al., 1999)

Secondary FlyBase IDs

References (1)

Report Sections

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