FB2026_02 , released June 18, 2026
Allele: Dmel\Kmn1G0237
Open Close
General Information
Symbol
Dmel\Kmn1G0237
Species
D. melanogaster
Name
FlyBase ID
FBal0098152
Feature type
allele
Associated gene
Dmel\Kmn1
Associated Insertion(s)
P{lacW}Kmn1G0237
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Schäfer et al., 1999.6.15)
Progenitor genotype
Associated Insertion(s)
P{lacW}Kmn1G0237
Cytology
Description

Insertion in the second exon, after codon 87.

(Venkei et al., 2011)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
AJ426866
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Cellularised mutant embryos contain body areas with lower cells densities than normal, in which cells have a high number of micronuclei and/or presumptive polyploid nuclei. Analysis of mitoses 15 and 16 in mutant embryos indicates that 2 broad categories of mitotic defect are seen; many cells show a pronounced delay in anaphase onset and chromosome mis-segregation is seen.

      (Venkei et al., 2011)

      Lethality occurs during the third larval instar. Third instar larvae are uncoordinated.

      (Peter et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      Comments
      Comments

      P{lacW} not verified as causing the lethality.

      (Schäfer et al., 1999.6.15)
      External Crossreferences and Linkouts ( 1 )
      Crossreferences
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      Kmn1G0237
      (Das et al., 2016, Popodi et al., 2010-)
      P1877
      (Meller and Rattner, 2002)
      l(1)G0237
      (Peter et al., 2002)
      l(1)G0237G0237
      nsl1P{lacW}G0237
      (Venkei et al., 2011)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)