FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\tshA3-2-66
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General Information
Symbol
Dmel\tshA3-2-66
Species
D. melanogaster
Name
FlyBase ID
FBal0099803
Feature type
allele
Associated gene
Dmel\tsh
Associated Insertion(s)
P{lacW}tshA3-2-66
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Salazar and Gomes, 1999)
Progenitor genotype
Associated Insertion(s)
P{lacW}tshA3-2-66
Cytology
Description

P{lacW} insertion upstream of the tsh transcription unit. This insertion causes a significant reduction in tsh transcript levels.

(Salazar and Gomes, 1999)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygotes/hemizygotes have ectopic vein material in the wing and have wing margin defects.

      Heterozygotes show a direct effect on the shape of the wing.

      (Dworkin and Gibson, 2006)

      Leaky allele. Mutants have a mitotic phenotype. tshA3-2-66/Df(2L)TW161 flies have drooping halteres and heldup wings.

      (Salazar and Gomes, 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Excision of the P{lacW} element results in reversion of the phenotype.

      (Salazar and Gomes, 1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      A3-2-66
      (Dworkin and Gibson, 2006)
      tshA3-2-66
      (Dworkin and Gibson., 2006)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)