FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Syx1A+t13.5
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General Information
Symbol
Dmel\Syx1A+t13.5
Species
D. melanogaster
Name
FlyBase ID
FBal0099814
Feature type
allele
Associated gene
Dmel\Syx1A
Associated Insertion(s)
Carried in Construct
P{syx1A+t13.5}
Key Links
Genomic Maps

Transgenic product class
genomic_DNA
(Wu et al., 1999)
wild_type
(Wu et al., 1999)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Wu et al., 1999)
wild_type
(Wu et al., 1999)
Mutagen
in vitro construct
(Wu et al., 1999)
Progenitor genotype
Carried in construct
P{syx1A+t13.5}
Cytology
Description

Contains a 13.5 kb XbaI genomic fragment including Syx1A transcription unit.

(Wu et al., 1999)
Allele components
Component
Use(s)
Regulatory region(s)
Syx1A
Encoded product / tool
Syx1A
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
3R:24,096,903..24,113,763 [-]
Linked to:
XbaI-XbaI restriction fragment
Comment:

Reported as a 13.5kb XbaI genomic fragment; the size of the fragment on the reference sequence is closer to 17kb. The position of the restriction fragment on the reference sequence was inferred by a FlyBase curator.

(Wu et al., 1999)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Syx1AΔ229 and Syx1A06737 flies rescued with Syx1A+t13.5, like wild-type, undergo peristaltic muscle contractions prior to hatching. They also show a robust response to tactile stimulation. Syx1AΔ229 embryos rescued with Syx1A+t13.5 exhibit wild-type cuticle phenotypes. Using whole-cell patch-clamp analysis Syx1AΔ229 homozygotes rescued by Syx1A+t13.5 show a robust evoked neurotransmission.

      (Wu et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Syx1A+t13.5 rescues Syx1AΔ229

      (Fergestad et al., 2001)

      Syx1A+t13.5 rescues Syx1AΔ229

      (Wu et al., 1999)

      Syx1A+t13.5 rescues Syx1A06737

      (Wu et al., 1999)
      Comments

      Rescues the lethality of Syx1AΔ229. Rescued embryos show normal spontaneous movement and response to touch.

      (Fergestad et al., 2001)

      Rescues Syx1AΔ229 to adult viability. Rescues Syx1A06737 to adult viability.

      (Wu et al., 1999)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Syx1A+t13.5
      syx1A+t13.5
      (Wu et al., 1999)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)