FlyBase Allele Report: Dmel\fz3[G10]

General Information

Symbol

Dmel\fz3^G10

Species

D. melanogaster

Name

FlyBase ID

FBal0101415

Feature type

allele

Associated gene

Dmel\fz3

Associated Insertion(s)

Carried in Construct

Also Known As

Dfz3^G10

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Sato et al., 1999)

Progenitor genotype

fz3^J29

(Sato et al., 1999)

Cytology

Description

Imprecise excision resulting in the deletion of fz3 DNA, including the transcription start site, the first exon and a portion of the intron.

(Sato et al., 1999)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

fertile

(Sato et al., 1999)

viable

(Sato et al., 1999)

Phenotype Manifest In

Detailed Description

Statement

Reference

Dorsal cluster neuron axon extension is not affected in the brains of fz3^G10 flies.

(Srahna et al., 2006)

Homozygotes have few appreciable morphological defects and planar polarity is normal.

(Sato et al., 1999)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

fz3^G10 is a suppressor of visible phenotype of wg¹/wg^l-17

(Sato et al., 1999)

wg¹/fz3^G10 is a suppressor of visible | dominant phenotype of ap^78j

(Sato et al., 1999)

fz3^G10 is a suppressor of visible | recessive phenotype of wg^en11

(Sato et al., 1999)

fz3^G10 is a suppressor of visible | recessive phenotype of wg^l-16

(Sato et al., 1999)

Other

Statement

Reference

fz3^G10, fz¹ has viable phenotype

(Sato et al., 1999)

fz3^G10, fz¹ has fertile phenotype

(Sato et al., 1999)

ap^78j, fz3^G10, wg¹ has visible | recessive phenotype

(Sato et al., 1999)

Phenotype Manifest In

Suppressor of

Statement

Reference

fz3^G10 is a suppressor of wing phenotype of wg¹/wg^l-17

(Sato et al., 1999)

wg¹/fz3^G10 is a suppressor of wing phenotype of ap^78j

(Sato et al., 1999)

fz3^G10 is a suppressor of antenna phenotype of wg^en11

(Sato et al., 1999)

fz3^G10 is a suppressor of antenna phenotype of wg^l-16

(Sato et al., 1999)

Other

Statement

Reference

ap^78j, fz3^G10, wg¹ has wing phenotype

(Sato et al., 1999)

Additional Comments

Genetic Interactions

Statement

Reference

The wingless phenotype of wg¹/wg^l-17 flies is partially rescued by fz3^G10; the fraction of flies with two wings increases from 46% to 87%, while the fraction of one wing and wingless flies reduces from 44% and 10% to 13% and 0.5% respectively. The wingless phenotype of wg¹ homozygotes is dominantly enhanced by ap^78j; no wing blade is formed at approximately 90% of presumptive wing-blade-forming sites. This phenotype is partially suppressed by fz3^G10. Most wg^l-16/wg^en11 flies lack antennal structures. This phenotype is significantly rescued by fz3^G10.

(Sato et al., 1999)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Dfz3^G10

(Chen et al., 2004, Sato et al., 1999)

fz3^G10

(Srahna et al., 2006)

fz3G10

(Schilling et al., 2014)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

Open Close