FlyBase Allele Report: Dmel\Gli[EP2306]

General Information

Symbol

Dmel\Gli^EP2306

Species

D. melanogaster

Name

FlyBase ID

FBal0101663

Feature type

allele

Associated gene

Dmel\Gli

Associated Insertion(s)

P{EP}Gli^EP2306

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Pena-Rangel et al., 2002, Gene Disruption Project members, 2001-, Kraut et al., 2001, Kraut et al., 2001, Abdelilah-Seyfried et al., 2000, Ashburner et al., 1999, Ashburner et al., 1999.10.12)

Progenitor genotype

Associated Insertion(s)

P{EP}Gli^EP2306

Cytology

Description

The P{EP} element is inserted 42 nucleotides 5' to the cDNA start.

(Kraut et al., 2001)

P{EP} insertion at -41bp relative to the start of the transcription unit.

(Abdelilah-Seyfried et al., 2000)

P{EP} 5' to Gli at position 17429 (Gli is from 17386 to 10808).

(Ashburner et al., 1999)

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2L:15,762,784..15,762,784 [-]

(Sharifkhodaei et al., 2016, Pena-Rangel et al., 2002, Gene Disruption Project members, 2001-, Kraut et al., 2001, Kraut et al., 2001, Abdelilah-Seyfried et al., 2000, Ashburner et al., 1999, Ashburner et al., 1999.10.12)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | larval stage, with Scer\GAL4^elav-C155

(Kraut et al., 2001)

visible, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

Phenotype Manifest In

anterior fascicle & synapse, with Scer\GAL4^elav-C155

(Kraut et al., 2001)

dorsocentral bristle, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

larval intersegmental nerve, with Scer\GAL4^elav-C155

(Kraut et al., 2001)

scutellar bristle, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

tormogen cell, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

Detailed Description

Statement

Reference

Mutant larvae expressing Gli^EP2306 under the control of Scer\GAL4^elav-C155 have reduced or abnormal synapses. Mutant larvae expressing Gli^EP2306 under the control of Scer\GAL4^elav-C155 have ISN neuron pathfinding defects.

(Kraut et al., 2001)

Expression of Gli^EP2306 under the control of Scer\GAL4^sca-537.4 results in the loss of a few scutellar or dorsocentral macrochaetae. Sensory organs with no socket and one shaft are seen.

(Abdelilah-Seyfried et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Gli^EP2306, Scer\GAL4^sca-537.4 has visible phenotype, enhanceable by H^E21

(Abdelilah-Seyfried et al., 2000)

Gli^EP2306, Scer\GAL4^sca-537.4 has visible phenotype, enhanceable by N^55e11

(Abdelilah-Seyfried et al., 2000)

Other

Statement

Reference

Gli^EP2306, Scer\GAL4^pnr-MD237, pnr^MD237/pnr[+] has lethal | pupal stage phenotype

(Pena-Rangel et al., 2002)

Gli^EP2306, Scer\GAL4^pnr-MD237, pnr^MD237 has lethal | pupal stage phenotype

(Pena-Rangel et al., 2002)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Selected as: a P{EP} insertion line that modifies the pnr^MD237/+ phenotype when expressed using Scer\GAL4^pnr-MD237.

(Pena-Rangel et al., 2002)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

EP(2)2306

(Abdelilah-Seyfried et al., 2000, Ashburner et al., 1999.10.12)

Gli^EP2306

(Sharifkhodaei et al., 2016)

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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